Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Kalyani, West Bengal, India.
Ann Afr Med. 2024 Jul 1;23(3):255-261. doi: 10.4103/aam.aam_63_23. Epub 2024 Jul 20.
The fifth edition of the WHO classification of tumors of the central nervous system (WHO CNS5) was published in 2021 which is the sixth version of the international standard for the diagnostics of CNS tumors. Regular updates of the consortium to inform molecular and practical approaches to CNS tumor taxonomy (cIMPACT-NOW) shaped the WHO CNS5 which continues the trend of incorporating the molecular characteristics of tumors into the histological and immunohistochemical findings. The various updates can be classified into general changes across all tumors and specific changes within the tumor groups. This mini-review highlights the general changes and the major changes in adult diffuse gliomas.
世界卫生组织(WHO)中枢神经系统肿瘤分类第五版(WHO CNS5)于 2021 年发布,这是中枢神经系统肿瘤诊断的第六个国际标准版本。为了向 CNS 肿瘤分类学通报分子和实际方法的联合体(cIMPACT-NOW)的定期更新塑造了 WHO CNS5,它延续了将肿瘤的分子特征纳入组织学和免疫组织化学发现的趋势。各种更新可以分为所有肿瘤的一般变化和肿瘤组内的具体变化。这篇迷你综述重点介绍了成人弥漫性神经胶质瘤的一般变化和主要变化。