2 型糖尿病患者的骨标志物评估。
Evaluation of Bone Markers in Type 2 Diabetes Mellitus.
机构信息
Department of Biochemistry, MRAMC, Ambedkar Nagar, Uttar Pradesh, India.
Department of Biochemistry, Prasad Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
出版信息
Ann Afr Med. 2024 Jul 1;23(3):324-327. doi: 10.4103/aam.aam_71_23. Epub 2024 Jul 20.
BACKGROUND
Diabetes mellitus (DM) has affected over 387 million patients globally, expected to reach 592 million by the end of 2035. It is a metabolic disorder characterized by chronic hyperglycemia caused by either insulin deficiency, insulin resistance, or both.
MATERIALS AND METHODS
The present study was designed to estimate the levels of different bone markers; serum Vitamin D, alkaline phosphatase, phosphorus, and calcium in patients with type 2 DM (T2DM). The study was conducted on patients aged 20-50 years diagnosed with T2DM, who were attending the outpatient/inpatient department of internal medicine.
RESULTS
The levels of calcium were decreased in the patients with diabetes and also the study proved a negative correlation between calcium and random plasma glucose (RPG). There was a significant negative correlation between RPG and serum 25(OH)D3.
CONCLUSION
We conclude that Vitamin D insufficiency is frequent in Moradabad, Uttar Pradesh. Sunshine exposure daily for 15 min on the face and hands is necessary to elevate the sunlight Vitamin D levels.
背景
全球有超过 3.87 亿糖尿病患者，预计到 2035 年底将达到 5.92 亿。它是一种代谢紊乱，其特征是由于胰岛素缺乏、胰岛素抵抗或两者兼而有之而导致的慢性高血糖。
材料和方法
本研究旨在评估 2 型糖尿病（T2DM）患者的不同骨标志物；血清维生素 D、碱性磷酸酶、磷和钙水平。该研究针对年龄在 20-50 岁、被诊断为 T2DM 的患者进行，他们在内科门诊/住院部就诊。
结果
糖尿病患者的血钙水平降低，研究还证明钙与随机血浆葡萄糖（RPG）之间呈负相关。RPG 与血清 25（OH）D3 之间存在显著负相关。
结论
我们的结论是，维生素 D 不足在北方邦莫拉达巴德很常见。每天在面部和手部接受 15 分钟的阳光照射是必需的，以提高阳光维生素 D 水平。
Zotero 插件