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南卡纳塔克邦2型糖尿病患者骨密度评估

Evaluation of bone mineral density among type 2 diabetes mellitus patients in South Karnataka.

作者信息

Asokan Athulya G, Jaganathan Jayakumar, Philip Rajeev, Soman Rino Roopak, Sebastian Shibu Thomas, Pullishery Fawaz

机构信息

Department of General Medicine, Pushpagiri Institute of Medical Sciences and Research Centre, Thiruvalla, Kerala, India.

Department of General Medicine, Kasturba Medical College, Mangalore, Karnataka, India.

出版信息

J Nat Sci Biol Med. 2017 Jan-Jun;8(1):94-98. doi: 10.4103/0976-9668.198363.

Abstract

BACKGROUND

Diabetes is one of the world's biggest health problems and the disease affects almost all organ systems. The relationship between type 2 diabetes mellitus (T2DM) and bone mineral density (BMD) has been controversial. Early identification of reduction in bone mass in a diabetic patient may be helpful in preventing the bone loss and future fracture risks.

OBJECTIVE

The aim is to study the effect of T2DM on BMD among patients in South Karnataka.

MATERIALS AND METHODS

A cross-sectional study was conducted on 150 patients between 40 and 70 years of age which included 75 diabetic and 75 nondiabetic subjects. BMD was measured using qualitative ultrasound and the data were compared among age-matched subjects of both the groups. Statistical analysis was performed using unpaired Student's -test and test of equality of proportions.

RESULTS

No significant difference was observed in bone density of both the groups. On further analyzing the data, incidence of osteoporosis was higher among diabetic subjects, whereas incidence of osteopenia was higher among nondiabetic subjects.

CONCLUSION

Although significant difference in bone mineral density was not observed in both the groups, the incidence of osteoporosis was higher among type 2 diabetics. Hence, all type 2 diabetics should be evaluated for the risk of osteoporosis and should be offered appropriate preventive measures.

摘要

背景

糖尿病是全球最大的健康问题之一,该疾病几乎影响所有器官系统。2型糖尿病(T2DM)与骨密度(BMD)之间的关系一直存在争议。早期识别糖尿病患者的骨量减少可能有助于预防骨质流失和未来的骨折风险。

目的

旨在研究T2DM对南卡纳塔克邦患者骨密度的影响。

材料与方法

对150名年龄在40至70岁之间的患者进行了一项横断面研究,其中包括75名糖尿病患者和75名非糖尿病患者。使用定性超声测量骨密度,并在两组年龄匹配的受试者之间比较数据。采用非配对学生t检验和比例相等检验进行统计分析。

结果

两组的骨密度均未观察到显著差异。进一步分析数据发现,糖尿病受试者中骨质疏松症的发生率较高,而非糖尿病受试者中骨量减少的发生率较高。

结论

尽管两组之间未观察到骨密度的显著差异,但2型糖尿病患者中骨质疏松症的发生率较高。因此,所有2型糖尿病患者都应评估骨质疏松症的风险,并应采取适当的预防措施。

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