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维生素C与癌症。这种关联有多令人信服?

Vitamin C and cancer. How convincing a connection?

作者信息

Yamanaka W K

出版信息

Postgrad Med. 1985 Nov 15;78(7):47-9, 52-3. doi: 10.1080/00325481.1985.11699204.

DOI:10.1080/00325481.1985.11699204
PMID:3903707
Abstract

More research is needed to draw definitive conclusions on the relationship between vitamin C intake and cancer, but the following general statements can be made. The effectiveness of megadoses (greater than 1 gm/day) of vitamin C for the cure or prevention of cancer is still unproven; in fact, the safety of megadoses is still in question. Therefore, they are not recommended for the general public at present and, if used at all, should be used under medical supervision. Epidemiologic evidence suggests that vitamin C-rich foods may be beneficial in preventing cancer, and their consumption should be encouraged as a measure to reduce the incidence of cancer. Well-controlled studies should be undertaken to elucidate the relationship between vitamin C and cancer, using both vitamin-containing foods and vitamin C supplements at different intake levels.

摘要

需要进行更多研究才能就维生素C摄入量与癌症之间的关系得出明确结论,但可以做出以下一般性陈述。大剂量(每天超过1克)维生素C用于治疗或预防癌症的有效性仍未得到证实;事实上,大剂量维生素C的安全性仍存在疑问。因此,目前不建议普通大众使用,如果要使用,也应在医疗监督下进行。流行病学证据表明,富含维生素C的食物可能有助于预防癌症,应鼓励食用这些食物以降低癌症发病率。应开展严格控制的研究,使用不同摄入量水平的含维生素食物和维生素C补充剂来阐明维生素C与癌症之间的关系。

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