• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

位于脑腹侧表面的5-羟色胺能神经元。

Serotonin neurons on the ventral brain surface.

作者信息

Gorcs T J, Liposits Z, Palay S L, Chan-Palay V

出版信息

Proc Natl Acad Sci U S A. 1985 Nov;82(21):7449-52. doi: 10.1073/pnas.82.21.7449.

DOI:10.1073/pnas.82.21.7449
PMID:3903754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC391362/
Abstract

Serotonin neurons and fibers on the subpial surface of the ventral medulla oblongata in the rat are described by immunohistochemistry and autoradiography. The neurons are concentrated in the area encompassed by the origins of the abducens, hypoglossal, glossopharyngeal, and vagus nerves. The highest number of serotonin surface neurons appears along the median medullary fissure or basilar sulcus, where they may represent the most ventral extensions of the raphe pallidus group. As these cells lie on the surface of the brain, they could be directly affected by alterations in the chemical composition of the cerebrospinal fluid and, depending on their connections, could influence important medullary functions.

摘要

采用免疫组织化学和放射自显影技术对大鼠延髓腹侧软膜表面的5-羟色胺神经元和纤维进行了描述。这些神经元集中在展神经、舌下神经、舌咽神经和迷走神经起始部所包围的区域。5-羟色胺表面神经元数量最多的部位出现在延髓正中裂或基底沟沿线,它们可能代表了中缝苍白球组最腹侧的延伸部分。由于这些细胞位于脑表面,它们可能会直接受到脑脊液化学成分变化的影响,并根据其连接情况,可能会影响延髓的重要功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/391362/13846b554d34/pnas00361-0304-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/391362/26e3cccee1dd/pnas00361-0303-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/391362/422d46b765a7/pnas00361-0304-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/391362/13846b554d34/pnas00361-0304-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/391362/26e3cccee1dd/pnas00361-0303-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/391362/422d46b765a7/pnas00361-0304-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/391362/13846b554d34/pnas00361-0304-b.jpg

相似文献

1
Serotonin neurons on the ventral brain surface.位于脑腹侧表面的5-羟色胺能神经元。
Proc Natl Acad Sci U S A. 1985 Nov;82(21):7449-52. doi: 10.1073/pnas.82.21.7449.
2
Distribution of tyrosine hydroxylase and neuropeptide Y-like immunoreactive neurons in rabbit medulla oblongata, with attention to colocalization studies, presumptive adrenaline-synthesizing perikarya, and vagal preganglionic cells.兔延髓中酪氨酸羟化酶和神经肽Y样免疫反应性神经元的分布,着重于共定位研究、假定的肾上腺素合成核周体以及迷走神经节前细胞。
J Comp Neurol. 1986 Jun 8;248(2):285-300. doi: 10.1002/cne.902480211.
3
Non-serotonergic origins of the dorsolateral funiculus in the rat ventral medulla.大鼠延髓腹侧背外侧索的非5-羟色胺能起源
J Neurosci. 1984 Mar;4(3):757-66. doi: 10.1523/JNEUROSCI.04-03-00757.1984.
4
Serotonin and substance P colocalization in medullary projections to the nucleus tractus solitarius: dual-colour immunohistochemistry combined with retrograde tracing.5-羟色胺与P物质在投射至孤束核的延髓神经纤维中的共定位:双色免疫组织化学结合逆行追踪法
J Chem Neuroanat. 1989 May-Jun;2(3):139-48.
5
Distribution of monoamine-containing terminals and fibers in the central nervous system of the chicken.鸡中枢神经系统中含单胺终末和纤维的分布
Jpn J Pharmacol. 1974 Dec;24(6):831-41. doi: 10.1254/jjp.24.831.
6
GABA-synthesizing neurons in the medulla: their relationship to serotonin-containing and spinally projecting neurons in the rat.延髓中γ-氨基丁酸合成神经元:它们与大鼠中含5-羟色胺神经元及脊髓投射神经元的关系
J Comp Neurol. 1991 Nov 8;313(2):349-67. doi: 10.1002/cne.903130210.
7
Distribution of neurons containing phenylethanolamine N-methyltransferase in medulla and hypothalamus of rat.大鼠延髓和下丘脑含苯乙醇胺N-甲基转移酶神经元的分布
J Comp Neurol. 1985 Sep 8;239(2):127-54. doi: 10.1002/cne.902390202.
8
Immunocytochemical studies of the 5-HT(1A) receptor in ventral medullaryneurons that project to the intermediolateral cell column and contain serotonin or tyrosine hydroxylase immunoreactivity.对投射至中间外侧细胞柱且含有5-羟色胺或酪氨酸羟化酶免疫反应性的延髓腹侧神经元中5-羟色胺(1A)受体的免疫细胞化学研究。
J Comp Neurol. 1997 Mar 10;379(2):261-70.
9
Termination patterns of serotoninergic medullary raphespinal fibers in the rat lumbar spinal cord: an anterograde immunohistochemical study.大鼠腰髓中5-羟色胺能延髓中缝脊髓纤维的终末模式:一项顺行免疫组织化学研究
J Comp Neurol. 1990 Jul 8;297(2):267-82. doi: 10.1002/cne.902970209.
10
Immunohistochemical and biochemical analysis of serotonin and substance P colocalization in the nucleus tractus solitarii and associated afferent ganglia of the rat.大鼠孤束核及相关传入神经节中5-羟色胺与P物质共定位的免疫组织化学和生化分析
Synapse. 1988;2(3):225-31. doi: 10.1002/syn.890020309.

引用本文的文献

1
Characteristic structures of serotonin neuron system. An immunohistochemical study.血清素神经元系统的特征性结构。一项免疫组织化学研究。
Histochemistry. 1988;88(3-6):497-500. doi: 10.1007/BF00570315.
2
Three-dimensional reconstruction of transmitter-identified central neurons by "en bloc" immunofluorescence histochemistry and confocal scanning microscopy.
Exp Brain Res. 1988;73(2):441-6. doi: 10.1007/BF00248236.
3
Serotonergic control of the hippocampus via local inhibitory interneurons.通过局部抑制性中间神经元对海马体的5-羟色胺能控制。

本文引用的文献

1
Immunohistochemical studies on the serotonergic innervation of the pia mater.软脑膜5-羟色胺能神经支配的免疫组织化学研究。
Histochemistry. 1982;76(2):277-80. doi: 10.1007/BF00501930.
2
Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals.大鼠中枢神经系统中5-羟色胺免疫反应性的分布——细胞体和终末
Neuroscience. 1981;6(4):557-618. doi: 10.1016/0306-4522(81)90146-9.
3
Central serotonergic nerves project to the pial vessels of the brain.中枢5-羟色胺能神经投射至脑的软脑膜血管。
Proc Natl Acad Sci U S A. 1990 Nov;87(21):8501-5. doi: 10.1073/pnas.87.21.8501.
Nature. 1983;306(5938):55-7. doi: 10.1038/306055a0.
4
Distribution of indolealkylamine nerve terminals in the ventricles of the rat brain.吲哚烷基胺神经末梢在大鼠脑室中的分布。
Z Zellforsch Mikrosk Anat. 1973 Nov 15;144(4):511-22. doi: 10.1007/BF00307377.
5
Antibodies to indolealkylamines: serotonin and melatonin.
Can J Biochem. 1974 Mar;52(3):196-202. doi: 10.1139/o74-032.
6
The unlabeled antibody enzyme method of immunohistochemistry: preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes.免疫组织化学的未标记抗体酶法:可溶性抗原-抗体复合物(辣根过氧化物酶-抗辣根过氧化物酶)的制备、性质及其在螺旋体鉴定中的应用
J Histochem Cytochem. 1970 May;18(5):315-33. doi: 10.1177/18.5.315.
7
Indoleamine neurons and their processes in the normal rat brain and in chronic diet-induced thiamine deficiency demonstrated by uptake of 3H-serotonin.通过3H-血清素摄取显示正常大鼠脑和慢性饮食诱导的硫胺素缺乏中的吲哚胺神经元及其突起。
J Comp Neurol. 1977 Dec 15;176(4):467-93. doi: 10.1002/cne.901760402.
8
Fine structure of labelled axons in the cerebellar cortex and nuclei of rodents and primates after intraventricular infusions with tritiated serotonin.脑室注射氚标记血清素后啮齿动物和灵长类动物小脑皮质及核团中标记轴突的精细结构
Anat Embryol (Berl). 1975 Dec 31;148(3):235-65. doi: 10.1007/BF00319846.
9
Serotonin axons in the supra- and subependymal plexuses and in the leptomeninges; their roles in local alterations of cerebrospinal fluid and vasomotor activity.室管膜上和室管膜下丛以及软脑膜中的5-羟色胺轴突;它们在脑脊液局部改变和血管舒缩活动中的作用。
Brain Res. 1976 Jan 30;102(1):103-30. doi: 10.1016/0006-8993(76)90578-3.
10
Serotonin and substance P coexist i, neurons of the rat's central nervous system.血清素和P物质共存于大鼠中枢神经系统的神经元中。
Proc Natl Acad Sci U S A. 1978 Mar;75(3):1582-6. doi: 10.1073/pnas.75.3.1582.