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基于移动医疗的行为干预对非裔美国产后超重或肥胖人群体重减轻和心血管代谢风险的影响:SnapBack 随机对照试验。

Efficacy of an mHealth-delivered behavioral intervention on weight loss and cardiometabolic risk in African American postpartum people with overweight or obesity: the SnapBack randomized controlled trial.

机构信息

Program for Maternal Health Equity, Center for Urban Bioethics, Department of Urban Health and Population Science, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.

Center for Obesity Research and Education, College of Public Health, Temple University, Philadelphia, Pennsylvania, USA.

出版信息

Obesity (Silver Spring). 2024 Sep;32(9):1646-1657. doi: 10.1002/oby.24091. Epub 2024 Jul 23.

Abstract

OBJECTIVE

The objective of this study was to evaluate the efficacy of a mobile health (mHealth)-delivered behavioral intervention on changes in postpartum weight and cardiometabolic risk factors (blood pressure [BP], lipids, and hemoglobin A1c) over 12 months.

METHODS

A randomized controlled trial of 300 African American postpartum people with overweight and obesity enrolled in Philadelphia Women, Infants, and Children (WIC) clinics was conducted. Participants were randomized to usual WIC care (n = 151) or a 12-month mHealth-delivered intervention (n = 149) comprising behavior change goals, interactive self-monitoring text messages, and counseling support.

RESULTS

Intervention and usual-care participants did not significantly differ in 12-month mean postpartum weight change (1.1 vs. 1.6 kg, p = 0.5; difference -0.6 kg, 95% CI: -2.3 to 1.2). However, high intervention engagement led to weight loss compared with weight gain among those who were less engaged (-0.6 vs. 2.4 kg, p = 0.01; difference -3.0 kg, 95% CI: -5.4 to -0.6). The intervention reduced systolic BP relative to usual care (-1.6 vs. 2.4 mm Hg, p = 0.02; difference -4.0 mm Hg, 95% CI: -7.5 to -0.5), but this effect did not extend to other cardiometabolic risk factors.

CONCLUSIONS

Among African American postpartum people enrolled in WIC, an mHealth-delivered intervention reduced systolic BP but not additional cardiometabolic risk factors or weight. Intervention participants with high engagement had significantly better postpartum weight outcomes, and thus, next steps include addressing barriers to engagement.

摘要

目的

本研究旨在评估通过移动健康(mHealth)提供的行为干预措施对产后体重和心血管代谢风险因素(血压[BP]、血脂和血红蛋白 A1c)在 12 个月内的变化的疗效。

方法

在费城妇女、婴儿和儿童(WIC)诊所招募了 300 名超重和肥胖的非裔美国产后人群,进行了一项随机对照试验。参与者被随机分配至接受常规 WIC 护理(n=151)或接受为期 12 个月的 mHealth 提供的干预(n=149),包括行为改变目标、互动自我监测短信和咨询支持。

结果

干预组和常规护理组在 12 个月后的产后体重变化平均值上没有显著差异(1.1 与 1.6kg,p=0.5;差值-0.6kg,95%CI:-2.3 至 1.2)。然而,高干预参与度导致体重减轻,而低参与度则导致体重增加(-0.6 与 2.4kg,p=0.01;差值-3.0kg,95%CI:-5.4 至-0.6)。与常规护理相比,该干预措施降低了收缩压(-1.6 与 2.4mmHg,p=0.02;差值-4.0mmHg,95%CI:-7.5 至-0.5),但这种效果并未扩展到其他心血管代谢风险因素。

结论

在参加 WIC 的非裔美国产后人群中,mHealth 提供的干预措施降低了收缩压,但没有改善其他心血管代谢风险因素或体重。具有高参与度的干预措施参与者的产后体重结果显著更好,因此,下一步包括解决参与障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fee9/11357893/09c9c89db92c/nihms-1995642-f0001.jpg

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