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使用压迫缝线和前房内注气治疗急性角膜水肿。

Management of Acute Corneal Hydrops Using Compression Sutures and Intracameral Air Injection.

机构信息

Anterior Segment Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.

出版信息

Am J Case Rep. 2024 Jul 23;25:e944517. doi: 10.12659/AJCR.944517.

Abstract

BACKGROUND Acute corneal hydrops, a rare complication of keratoconus, is characterized by sudden onset of corneal stroma edema. It typically manifests as an acute decrease in visual acuity, accompanied by pain and photophobia. Prompt recognition and interventions are critical for effective resolution of hydrops and prevention of corneal vascularization. Herein, we present a case of a patient with keratoconus who developed corneal hydrops, successfully managed using full-thickness compression sutures and intracameral air injection. CASE REPORT A woman in her early 30s, with a history of keratoconus, presented with symptoms of acute hydrops in her left eye. On presentation, best corrected visual acuity was hand motion. Slit-lamp examination revealed marked corneal edema with multiple stromal clefts. The decision was made to perform full-thickness compression sutures combined with intracameral air injection to expedite edema resolution and prevent neovascularization. Three full-thickness sutures were placed across Descemet membrane breaks, and an air bubble was left, filling 50% of the anterior chamber. At 3-month follow-up, a clear, compact cornea was noted, with no evidence of vascularization. The patient was scheduled for penetrating keratoplasty for visual rehabilitation. CONCLUSIONS The combination of full-thickness compression sutures and intracameral air seems to be an effective and safe method for preventing corneal angiogenesis following hydrops. As corneal scaring is often an inevitable complication of acute corneal hydrops, keratoplasty is necessary for improving visual acuity. Hence, the prevention of corneal vascularization should be the major aim in the management of corneal hydrops to ensure successful keratoplasty.

摘要

背景

急性角膜水肿是圆锥角膜的一种罕见并发症,其特征为角膜基质突然水肿。它通常表现为视力急剧下降,伴有疼痛和畏光。及时识别和干预对于有效解决水肿和预防角膜血管化至关重要。在此,我们报告了一例圆锥角膜患者发生角膜水肿,成功地通过全层压缩缝线和前房内空气注射进行治疗。

病例报告

一名 30 岁出头的女性,有圆锥角膜病史,左眼出现急性水肿症状。就诊时,最佳矫正视力为手动。裂隙灯检查显示明显的角膜水肿,伴有多个基质裂。决定行全层压缩缝线联合前房内空气注射,以加速水肿消退并预防新生血管形成。在 3 个全层缝线穿过 Descemet 膜破裂处,并留下一个气泡,填充前房的 50%。在 3 个月的随访时,角膜清晰、紧凑,无血管化证据。患者计划进行穿透性角膜移植以恢复视力。

结论

全层压缩缝线联合前房内空气似乎是预防水肿后角膜血管化的有效且安全的方法。由于角膜瘢痕常常是急性角膜水肿的不可避免的并发症,因此对于改善视力,角膜移植是必要的。因此,在管理角膜水肿时,预防角膜血管化应该是主要目标,以确保角膜移植的成功。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bc3/11299868/ad4c38583f7b/amjcaserep-25-e944517-g001.jpg

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