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坏死梭杆菌对非洲绿猴肾细胞的黏附

Adherence of Fusobacterium necrophorum to Vero cells.

作者信息

Kanoe M, Nagai S, Toda M

出版信息

Zentralbl Bakteriol Mikrobiol Hyg A. 1985 Aug;260(1):100-7. doi: 10.1016/s0176-6724(85)80104-8.

DOI:10.1016/s0176-6724(85)80104-8
PMID:3904278
Abstract

The adherence of the anaerobic species Fusobacterium necrophorum to the surface of Vero cells was studied. Adherence between the bacterium and the tissue culture cells was paralleled by the hemagglutinability of F. necrophorum. Treatment of the bacterial cells with lactoalbumin hydrolysate or anti-F. necrophorum-hemagglutinin serum reduced the intensity of the attachment. The purified hemagglutinin bound to the membranes of Vero cells. It lost its adherent property when mixed with the homologous anti-hemagglutinin serum. These observations suggest that the adherence of F. necrophorum to the surface of Vero cells is mediated by the bacterial hemagglutinin.

摘要

研究了坏死梭杆菌这种厌氧菌对Vero细胞表面的黏附情况。该细菌与组织培养细胞之间的黏附情况与坏死梭杆菌的血凝活性相似。用乳白蛋白水解物或抗坏死梭杆菌血凝素血清处理细菌细胞会降低黏附强度。纯化的血凝素能与Vero细胞的膜结合。当与同源抗血凝素血清混合时,它会失去黏附特性。这些观察结果表明,坏死梭杆菌对Vero细胞表面的黏附是由细菌血凝素介导的。

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引用本文的文献

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Fusobacterium necrophorum infections: virulence factors, pathogenic mechanism and control measures.坏死梭杆菌感染:毒力因子、致病机制及控制措施
Vet Res Commun. 1996;20(2):113-40. doi: 10.1007/BF00385634.