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tRF-Glu-TTC-026 as novel diagnostic biomarkers for active tuberculosis and regulates intracellular survival of Mycobacterium tuberculosis in macrophages by regulating macrophage polarization.

作者信息

Huang Zikun, Xiong Cuifen, Luo Qing, Zhu Juxiang, Guo Yongqin, Fu Peng, Zhu Haiyan, Xu Jianqing, Guo Yang, Peng Yiping, Qing Cheng, Li Junming, Le Aiping

机构信息

Department of Clinical Laboratory, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.

Nanchang Key Laboratory of Diagnosis of Infectious Diseases, Gaoxin Branch Of The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.

出版信息

Clin Transl Med. 2024 Jul;14(7):e1781. doi: 10.1002/ctm2.1781.

DOI:10.1002/ctm2.1781
PMID:39043626
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11265989/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/11265989/8f1e99a9e126/CTM2-14-e1781-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/11265989/2750c1873b30/CTM2-14-e1781-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/11265989/20df1147ed5c/CTM2-14-e1781-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/11265989/ea97ffe0b66e/CTM2-14-e1781-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/11265989/8f1e99a9e126/CTM2-14-e1781-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/11265989/2750c1873b30/CTM2-14-e1781-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/11265989/20df1147ed5c/CTM2-14-e1781-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/11265989/ea97ffe0b66e/CTM2-14-e1781-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee6/11265989/8f1e99a9e126/CTM2-14-e1781-g004.jpg

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Clin Transl Med. 2023 Feb;13(2):e1194. doi: 10.1002/ctm2.1194.
2
A novel tRNA-derived fragment tRF-3022b modulates cell apoptosis and M2 macrophage polarization via binding to cytokines in colorectal cancer.一种新型 tRNA 衍生片段 tRF-3022b 通过与结直肠癌中的细胞因子结合调节细胞凋亡和 M2 巨噬细胞极化。
J Hematol Oncol. 2022 Dec 16;15(1):176. doi: 10.1186/s13045-022-01388-z.
3
Estimating annual risk of infection with Mycobacterium tuberculosis.
估计结核分枝杆菌的年度感染风险。
Lancet Infect Dis. 2022 Sep;22(9):1276-1277. doi: 10.1016/S1473-3099(22)00454-6.
4
Deciphering the tRNA-derived small RNAs: origin, development, and future.解析 tRNA 衍生的小 RNA：起源、发展与未来。
Cell Death Dis. 2021 Dec 21;13(1):24. doi: 10.1038/s41419-021-04472-3.
5
tRNA-derived small RNAs: novel regulators of cancer hallmarks and targets of clinical application.转运RNA衍生的小RNA：癌症特征的新型调节因子及临床应用靶点
Cell Death Discov. 2021 Sep 18;7(1):249. doi: 10.1038/s41420-021-00647-1.
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Validation of a host blood transcriptomic biomarker for pulmonary tuberculosis in people living with HIV: a prospective diagnostic and prognostic accuracy study.宿主血液转录组生物标志物对 HIV 感染者肺结核的诊断和预后评估的验证：一项前瞻性诊断和预后准确性研究。
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7
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