SUNY Upstate Medical University, Syracuse, NY, USA.
J Investig Med High Impact Case Rep. 2024 Jan-Dec;12:23247096241263536. doi: 10.1177/23247096241263536.
Primary pancreatic lymphomas (PPLs) are a subgroup of gastrointestinal (GI) lymphomas. They are an exceedingly rare entity, both in terms of pancreatic malignancies and also extranodal lymphomas. Epidemiological investigations have been challenging to do because of their rarity. This has resulted in a lack of clarity on the clinicopathological characteristics, differential diagnosis, best course of treatment, and prognosis of PPL. Because the clinical signs are frequently non-specific, it can lead to a diagnostic hazard for the unwary physician. Preoperatively, it is imperative to distinguish between adenocarcinoma and PPL, as they present similarly, but have vastly different treatment modalities and prognosis. We herein present a case of an elderly man who presented with obstructive jaundice and was found to have PPL.
原发性胰腺淋巴瘤(PPL)是胃肠道(GI)淋巴瘤的一个亚组。无论是胰腺恶性肿瘤还是结外淋巴瘤,它们都是一种极其罕见的实体。由于其罕见性,进行流行病学研究一直具有挑战性。这导致 PPL 的临床病理特征、鉴别诊断、最佳治疗方案和预后仍不明确。由于临床症状常常不具有特异性,因此可能会给粗心的医生带来诊断风险。术前,必须区分腺癌和 PPL,因为它们的表现相似,但治疗方式和预后却大不相同。在此,我们报告了一例老年男性,因阻塞性黄疸就诊,被诊断为 PPL。