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从尼泊尔加德满都谷地采集的药用花卉拉利古兰的抗氧化和抗菌活性

Antioxidant and Antibacterial Activities of Medicinal Flower Laligurans Collected from Kathmandu Valley, Nepal.

作者信息

Jha Anil Kumar, Khalid Monowar Alam, Labh Shyam Narayan

机构信息

Department of Environment Science Integral University, Kursi Road 226026, Lucknow, Uttar Pradesh, India.

Aquaculture Research Unit Amrit Science Campus Tribhuvan University, Kathmandu 44600, Nepal.

出版信息

Int J Food Sci. 2024 Jul 16;2024:6073042. doi: 10.1155/2024/6073042. eCollection 2024.

Abstract

, known as Nepal's national flower and belonging to the Ericaceae family, thrives throughout the Himalayan region. This study investigates the antioxidant and antimicrobial potential of flowers. Three different extracts were prepared at concentrations ranging from 10 to 640 g/mL and assessed for their total phenolic content (TPC), total flavonoid content (TFC), and DPPH radical scavenging activity. Results showed significant accumulation of antioxidant compounds ( < 0.05), with TPC levels of 37.78, 67.29, and 53.46 mg GAE/g and TFC values of 49.46, 67.46, and 65.71 mg QE/g for LGP, LGE, and LGA at 640 g/mL, respectively. DPPH activity was highest in LGE (96.33%), followed by LGA (87.11%) and LGP (76.59%), compared to the standard (77.38%). The antibacterial properties were significant against , , and at 100% concentration, with inhibition rates of 15%, 16%, and 17% for LGP, LGE, and LGA, respectively. These findings indicate that petals, rich in bioactive compounds, possess strong antioxidant and antibacterial properties, making them potential candidates for developing cost-effective therapeutic formulations. Further research should focus on isolating specific bioactive compounds and understanding their molecular mechanisms to enhance therapeutic efficacy.

摘要

被誉为尼泊尔国花且属于杜鹃花科的[花名],在整个喜马拉雅地区生长繁茂。本研究调查了[花名]花的抗氧化和抗菌潜力。制备了浓度范围为10至640 g/mL的三种不同提取物,并评估了它们的总酚含量(TPC)、总黄酮含量(TFC)和DPPH自由基清除活性。结果显示抗氧化化合物有显著积累(<0.05),在640 g/mL时,LGP、LGE和LGA的TPC水平分别为37.78、67.29和53.46 mg GAE/g,TFC值分别为49.46、67.46和65.71 mg QE/g。与标准品(77.38%)相比,LGE的DPPH活性最高(96.33%),其次是LGA(87.11%)和LGP(76.59%)。在100%浓度下,对[细菌名]、[细菌名]和[细菌名]的抗菌性能显著,LGP、LGE和LGA的抑制率分别为15%、16%和17%。这些发现表明,富含生物活性化合物的[花名]花瓣具有很强的抗氧化和抗菌性能,使其成为开发具有成本效益的治疗制剂的潜在候选物。进一步的研究应集中在分离特定的生物活性化合物并了解其分子机制,以提高治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1734/11265945/6612f593e24a/IJFS2024-6073042.001.jpg

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