Xu Duojie, Yuan Ling, Meng Fandi, Lu Doudou, Che Mengying, Yang Yating, Liu Wenjing, Nan Yi
Traditional Chinese Medicine College, Ningxia Medical University, Yinchuan, Ningxia, China.
College of Pharmacy, Ningxia Medical University, Yinchuan, Ningxia, China.
Front Nutr. 2024 Jul 9;11:1430768. doi: 10.3389/fnut.2024.1430768. eCollection 2024.
Sea buckthorn (), as a homologous species of medicine and food, is widely used by Mongolians and Tibetans for its anti-tumor, antioxidant and liver-protecting properties. In this review, the excellent anti-tumor effect of sea buckthorn was first found through network pharmacology, and its active components such as isorhamnetin, quercetin, gallic acid and protocatechuic acid were found to have significant anti-tumor effects. The research progress and application prospect of sea buckthorn and its active components in anti-tumor types, mechanism of action, liver protection, anti-radiation and toxicology were reviewed, providing theoretical basis for the development of sea buckthorn products in the field of anti-tumor research and clinical application.
沙棘作为药食同源的物种，因其抗肿瘤、抗氧化和保肝特性而被蒙古族和藏族广泛使用。在本综述中，首先通过网络药理学发现了沙棘具有优异的抗肿瘤作用，并发现其活性成分如异鼠李素、槲皮素、没食子酸和原儿茶酸具有显著的抗肿瘤作用。综述了沙棘及其活性成分在抗肿瘤类型、作用机制、保肝、抗辐射和毒理学方面的研究进展及应用前景，为沙棘产品在抗肿瘤研究和临床应用领域的开发提供理论依据。
