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体外膜肺氧合治疗儿童患者难治性颅内压升高的管理:病例分析。

Managing medically refractory elevated intracranial pressure in a pediatric patient on ECMO: illustrative case.

机构信息

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

Childs Nerv Syst. 2024 Nov;40(11):3843-3847. doi: 10.1007/s00381-024-06549-8. Epub 2024 Jul 24.

Abstract

PURPOSE

We demonstrate the complexities of managing pediatric patients on extracorporeal membrane oxygenation (ECMO) therapy requiring neurosurgery, focusing on systemic anticoagulation, cardiac function, and medically refractory intracranial pressure (ICP).

METHODS

A 3.5-year-old female with Tetralogy of Fallot developed severe ischemic cerebral edema following post-operative cardiac arrest and required ECMO. This case, along with four additional cases of children requiring neurosurgery while on ECMO, was examined.

RESULTS

Emergency neurosurgical intervention in the primary case led to significant improvement, highlighting the delicate balance between managing ECMO-induced anticoagulation and urgent neurosurgical needs. The additional cases had variable outcomes, emphasizing the challenges of caring for these critically ill patients.

CONCLUSION

Successful management of children requiring ECMO support and neurosurgical intervention requires thoughtful multidisciplinary care. This report illustrates some of the nuances in such decision-making, and demonstrates one potential path to a good outcome.

摘要

目的

我们展示了在体外膜肺氧合(ECMO)治疗中需要神经外科治疗的儿科患者管理的复杂性,重点关注全身抗凝、心脏功能和药物难治性颅内压(ICP)。

方法

一名 3.5 岁的女性患有法洛四联症,术后心脏骤停后出现严重的缺血性脑水肿,需要 ECMO。本案例以及另外 4 例 ECMO 期间需要神经外科治疗的儿童案例进行了研究。

结果

在原发性病例中进行紧急神经外科干预导致显著改善,突出了管理 ECMO 诱导的抗凝和紧急神经外科需求之间的微妙平衡。其他病例的结果存在差异,强调了照顾这些重症患者的挑战。

结论

成功管理需要 ECMO 支持和神经外科干预的儿童需要深思熟虑的多学科护理。本报告说明了此类决策中的一些细微差别,并展示了一种可能的良好结果途径。

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