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添加还原氧化石墨烯的丙烯酸树脂的微观结构表征、力学性能和微生物性能

Microstructural characterization, mechanical and microbiological properties of acrylic resins added with reduced graphene oxide.

作者信息

Sahm Beatriz Danieletto, Ferreira Izabela, Carvalho-Silva João Marcos, Teixeira Ana Beatriz Vilela, Teixeira Jean Valdir Uchôa, Lisboa-Filho Paulo Noronha, Dos Reis Andréa Cândido

机构信息

Department of Dental Materials and Prosthesis, Ribeirão Preto School of Dentistry, University of São Paulo (USP), FORP-USP. Av. Do Café, s/n, Ribeirão Preto, SP, 14040-904, Brazil.

Paulista State University Júlio de Mesquita Filho (UNESP), Bauru, SP, Brazil.

出版信息

Odontology. 2025 Jan;113(1):340-348. doi: 10.1007/s10266-024-00981-7. Epub 2024 Jul 24.

Abstract

To evaluate the microstructural characterization, mechanical properties and antimicrobial activity of acrylic resins incorporated with different concentrations of reduced graphene oxide (rGO). Specimens were made of self-cured and heat-cured acrylic resins for the control group and concentrations of 0.5%, 1%, and 3%. The microstructural characterization was evaluated by scanning electron microscopy (SEM) and energy-dispersive X-ray (EDS). For mechanical testing, flexural strength, and Knoop hardness tests were performed. Microbiological evaluations were performed by colony forming units (CFU) analysis, tetrazolium salt reduction (XTT), and SEM images. The modified acrylic resins showed increased mechanical properties at low concentrations (p < 0.05) and with reduced S. mutans (p < 0.05). Reduced graphene oxide interfered with the mechanical performance and microbiological properties of acrylic resins depending on the concentration of rGO, and type of polymerization and microorganism evaluated. The incorporation of graphene compounds into acrylic resins is an alternative to improve the antimicrobial efficacy and performance of the material.

摘要

评估不同浓度还原氧化石墨烯(rGO)掺入的丙烯酸树脂的微观结构特征、力学性能和抗菌活性。对照组以及0.5%、1%和3%浓度组的样本由自固化和热固化丙烯酸树脂制成。通过扫描电子显微镜(SEM)和能量色散X射线(EDS)评估微观结构特征。进行力学测试时,进行了弯曲强度和努氏硬度测试。通过菌落形成单位(CFU)分析、四氮唑盐还原(XTT)和SEM图像进行微生物学评估。改性丙烯酸树脂在低浓度下力学性能增强(p < 0.05),变形链球菌数量减少(p < 0.05)。根据rGO的浓度、聚合类型和所评估的微生物,还原氧化石墨烯会干扰丙烯酸树脂的力学性能和微生物学性能。将石墨烯化合物掺入丙烯酸树脂是提高材料抗菌功效和性能的一种替代方法。

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