Arian Arvin, Roostaei Ghazal, Rasoulighasemlouei Seyede Sahel, Alborzi Avanaki Foroogh, Daryani Nasser Ebrahimi
Department of Internal Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Middle East J Dig Dis. 2024 Jan;16(1):23-27. doi: 10.34172/mejdd.2024.364. Epub 2024 Jan 31.
The goal of this study was to evaluate magnetic resonance enterography (MRE) findings and assess the role of diffusion-weighted imaging (DWI) in patients suffering from active Crohn's disease.
This retrospective study included a total number of 76 patients diagnosed with active Crohn's disease, as established by the Crohn's Disease Activity Index (CDAI). The study consisted of 30 women and 46 men, ranging in age from 13 to 72 years. All participants underwent MRE with DWI sequences. The study was conducted at Imam Khomeini hospital in Tehran between 2013 and 2018. The imaging modality utilized for the study included a 3-T SIGNA Excite MRE machine and a Siemens Magnetom 3-T magnetic resonance imaging (MRI) machine.
Bowel wall restriction was observed in less than half of the patients, and no significant correlation was found with extramural findings such as mesenteric edema. The study did not reveal any meaningful association between diffusion restriction and specific mural enhancement patterns, mesenteric lymphadenopathy with or without enhancement, or the length of the affected segments (>0.05). The most common findings observed in MRI were ileum thickness in 72.4% of patients, mesenteric lymphadenopathy without enhancement in 46.1%, ileocecal thickness in 42.1%, DWI findings in 42.1%, the presence of a comb sign in 36.8%, and jejunum thickness in 30.3% of patients.
MRE findings are useful in the evaluation of Crohn's disease activity.
本研究的目的是评估磁共振小肠造影（MRE）的结果，并评估扩散加权成像（DWI）在活动性克罗恩病患者中的作用。
这项回顾性研究共纳入76例经克罗恩病活动指数（CDAI）确诊为活动性克罗恩病的患者。研究包括30名女性和46名男性，年龄在13至72岁之间。所有参与者均接受了带有DWI序列的MRE检查。该研究于2013年至2018年在德黑兰的伊玛目霍梅尼医院进行。本研究使用的成像设备包括一台3-T SIGNA Excite MRE机器和一台西门子Magnetom 3-T磁共振成像（MRI）机器。
不到一半的患者观察到肠壁受限，且未发现与肠系膜水肿等肠壁外表现有显著相关性。该研究未发现扩散受限与特定的肠壁强化模式、有无强化的肠系膜淋巴结肿大或受累节段长度之间存在任何有意义的关联（>0.05）。MRI中观察到的最常见表现为72.4%的患者回肠增厚、46.1%的患者无强化的肠系膜淋巴结肿大、42.1%的患者回盲部增厚、42.1%的患者有DWI表现、36.8%的患者有梳征以及30.3%的患者空肠增厚。
MRE结果有助于评估克罗恩病的活动度。
