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抑郁在肺部疾病与心血管健康关联中的中介作用。

The mediating effect of depression on the association between lung disease and cardiovascular health.

作者信息

Chen Feng, Lin Hao, Zhang Yuansi, Zhang Yu, Yang Enhui

机构信息

Department of Child Healthcare, Wenzhou People's Hospital, Wenzhou, Zhejiang Province, China.

Children's Heart Center, The Second Hospital and Yuying Children's Hospital, Institute of Cardiovascular Development and Translational Medicine, Wenzhou Medical University, Zhejiang, China.

出版信息

Arch Med Sci. 2024 Jun 30;20(3):1029-1033. doi: 10.5114/aoms/189973. eCollection 2024.

Abstract

INTRODUCTION

In this study, we investigated the effect of depression on the interaction between lung disease and cardiovascular health (CVH).

METHODS

Utilising data from the National Health and Nutrition Examination Survey (2013-2018), we employed multivariate regression and bootstrap mediation analysis to explore the relationships among lung diseases, depression, and CVH scores.

RESULTS

Complex and significant associations were identified among lung diseases, depression, and CVH scores, with depression mediating 9.42% of the effect on CVH, especially for chronic bronchitis patients.

CONCLUSIONS

Depression significantly mediated the relationship between lung disease and reduced CVH scores, highlighting the importance of mental health management in lung disease patients.

摘要

引言

在本研究中,我们调查了抑郁症对肺部疾病与心血管健康(CVH)之间相互作用的影响。

方法

利用国家健康与营养检查调查(2013 - 2018年)的数据,我们采用多元回归和引导中介分析来探究肺部疾病、抑郁症和CVH评分之间的关系。

结果

在肺部疾病、抑郁症和CVH评分之间发现了复杂且显著的关联,抑郁症介导了对CVH影响的9.42%,尤其是对慢性支气管炎患者。

结论

抑郁症显著介导了肺部疾病与CVH评分降低之间的关系,突出了肺部疾病患者心理健康管理的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5168/11264099/12f578e8254d/AMS-20-3-189973-g001.jpg

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