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音乐疗法联合习惯逆转训练对抽动障碍儿童的影响:一项回顾性研究。

Effects of Music Therapy Combined with Habit Reversal Training on Children with Tic Disorders: A Retrospective Study.

作者信息

Liu Yali, Chang Haixia, Li Xiulin, Zhang Mingjing, Wang Xia

机构信息

Department of Child Health, Hebei Children's Hospital Affiliated to Hebei Medical University, Shijiazhuang 050000, Hebei, China.

出版信息

Noise Health. 2025;27(125):104-111. doi: 10.4103/nah.nah_195_24. Epub 2025 Apr 29.

Abstract

UNLABELLED

Objective This study aimed to investigate the effects of music therapy combined with habit reversal training (HRT) on children with tic disorders.

METHODS

A retrospective study was conducted on the clinical data of 122 children diagnosed with chronic tic disorders admitted to Hebei Children's Hospital Affiliated to Hebei Medical University from January 2021 to January 2024. According to different treatment methods, patients were separated into the HRT group (n = 55), who received routine HRT, and the music therapy group (n = 67), who received music therapy combined with HRT. The baseline data before treatment and the clinical efficacy after 8 weeks of treatment of the two groups were compared. Before and after the 8-week treatment, the Yale Global Tic Severity Scale (YGTSS) scores, serum neurotransmitter levels, Child Behavior Checklist (CBCL), and Pediatric Quality of Life Inventory (PedsQL) were compared between the two groups.

RESULTS

After an 8-week treatment, the Global Severity Score and Total Tic Score of YGTSS significantly decreased in both groups, with the music therapy group showing lower scores than the HRT group (P < 0.05). The total effective rate in the music therapy group was higher than that in the HRT group (92.54% vs. 80.00%, P < 0.05). Serum dopamine and serotonin levels significantly decreased after treatment in both groups, with the music therapy group showing lower levels than the HRT group (P < 0.05). Conversely, serum γ-aminobutyric acid levels significantly increased after treatment in both groups, with the music therapy group showing higher levels than the HRT group (P < 0.05). The CBCL and PedsQL scores significantly improved after treatment in both groups, with the music therapy group showing a significant decrease in CBCL scores and a significant increase in PedsQL scores compared with the HRT group (P < 0.05).

CONCLUSION

Music therapy combined with HRT significantly enhanced treatment efficacy for children with tic disorders. It reduced tic severity, improved behavioral outcomes, and modulated neurotransmitter levels. The study demonstrated the potential clinical value of music therapy as a nonpharmacological treatment for tic disorders.

摘要

未标注

目的 本研究旨在探讨音乐疗法联合习惯逆转训练(HRT)对抽动障碍儿童的影响。

方法

对2021年1月至2024年1月在河北医科大学附属河北儿童医院收治的122例诊断为慢性抽动障碍的儿童临床资料进行回顾性研究。根据不同治疗方法,将患者分为接受常规HRT的HRT组(n = 55)和接受音乐疗法联合HRT的音乐疗法组(n = 67)。比较两组治疗前的基线数据和治疗8周后的临床疗效。在8周治疗前后,比较两组的耶鲁全球抽动严重程度量表(YGTSS)评分、血清神经递质水平、儿童行为量表(CBCL)和儿童生活质量量表(PedsQL)。

结果

经过8周治疗,两组YGTSS的总体严重程度评分和抽动总分均显著降低,音乐疗法组的评分低于HRT组(P < 0.05)。音乐疗法组的总有效率高于HRT组(92.54%对80.00%,P < 0.05)。两组治疗后血清多巴胺和5-羟色胺水平均显著降低,音乐疗法组的水平低于HRT组(P < 0.05)。相反,两组治疗后血清γ-氨基丁酸水平均显著升高,音乐疗法组的水平高于HRT组(P < 0.05)。两组治疗后CBCL和PedsQL评分均显著改善,与HRT组相比,音乐疗法组的CBCL评分显著降低,PedsQL评分显著升高(P < 0.05)。

结论

音乐疗法联合HRT显著提高了抽动障碍儿童的治疗效果。它降低了抽动严重程度,改善了行为结果,并调节了神经递质水平。该研究证明了音乐疗法作为抽动障碍非药物治疗方法的潜在临床价值。

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