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刚果民主共和国一名年轻成年人的原发性水痘感染:病例报告与简要综述

Primary Varicella Infection in a Young Adult from the Democratic Republic of the Congo: A Case Report and Mini-Review.

作者信息

McNaughton Andrew, Karsenti Nessika, Kwan Jason, Adawi Asal, Mansuri Saniya, Boggild Andrea K

机构信息

Department of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.

Department of Medicine, Memorial University, Saint John's, NF A1B 3V6, Canada.

出版信息

Infect Dis Rep. 2024 Jul 19;16(4):628-637. doi: 10.3390/idr16040048.

DOI:10.3390/idr16040048
PMID:39051248
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11270367/
Abstract

We describe a case of an immunocompetent adult male patient originally from the Democratic Republic of Congo (DRC), who was referred to our unit for a several-day history of fever and a pruritic, vesicular rash. There was initial concern in the Emergency Department for Mpox (formerly known as "monkeypox") given the current epidemiology versus other viral etiologies. Primary varicella zoster virus (pVZV) infection was ultimately diagnosed by PCR from a swabbed, unroofed lesion, and he recovered completely with supportive management and without antiviral therapy. We herein describe how common viral exanthems may best be differentiated in an emergency or outpatient setting.

摘要

我们描述了一例免疫功能正常的成年男性患者,他来自刚果民主共和国(DRC),因发热、瘙痒性水疱皮疹数天的病史被转诊至我们科室。鉴于当前的流行病学情况与其他病毒病因相比,急诊科最初担心是猴痘(以前称为“猴天花”)。最终通过对一个擦拭、去除疱顶的皮损进行PCR检测诊断为原发性水痘带状疱疹病毒(pVZV)感染,他通过支持性治疗完全康复,未接受抗病毒治疗。我们在此描述在急诊或门诊环境中如何最好地鉴别常见的病毒疹。

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本文引用的文献

1
Primary varicella in 2 adult immigrants to Canada.2名成年加拿大移民中的原发性水痘。
CMAJ. 2023 Feb 27;195(8):E300-E303. doi: 10.1503/cmaj.220951.
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Monkeypox.猴痘。
Lancet. 2023 Jan 7;401(10370):60-74. doi: 10.1016/S0140-6736(22)02075-X. Epub 2022 Nov 17.
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Clinical Manifestations of Varicella: Disease Is Largely Forgotten, but It's Not Gone.水痘的临床表现:这种疾病已被淡忘,但并未消失。
J Infect Dis. 2022 Oct 21;226(Suppl 4):S380-S384. doi: 10.1093/infdis/jiac390.
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Measles.麻疹。
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A Tale of Two Viruses: Coinfections of Monkeypox and Varicella Zoster Virus in the Democratic Republic of Congo.《两种病毒的故事:刚果民主共和国的猴痘和水痘带状疱疹病毒合并感染》。
Am J Trop Med Hyg. 2020 Dec 7;104(2):604-611. doi: 10.4269/ajtmh.20-0589.
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Modelling human-to-human transmission of monkeypox.猴痘人际传播建模。
Bull World Health Organ. 2020 Sep 1;98(9):638-640. doi: 10.2471/BLT.19.242347. Epub 2020 Jul 8.
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Hand-Foot-and-Mouth Disease: Rapid Evidence Review.手足口病:快速证据综述。
Am Fam Physician. 2019 Oct 1;100(7):408-414.
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Varicella in Tshuapa Province, Democratic Republic of Congo, 2009-2014.2009-2014 年刚果民主共和国下刚果省的水痘疫情。
Trop Med Int Health. 2019 Jul;24(7):839-848. doi: 10.1111/tmi.13243. Epub 2019 May 22.
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Epidemiology and factors influencing varicella infections in tropical countries including Sri Lanka.包括斯里兰卡在内的热带国家水痘感染的流行病学及影响因素。
Virusdisease. 2018 Sep;29(3):277-284. doi: 10.1007/s13337-018-0459-z. Epub 2018 Jul 6.
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No. 274-Management of Varicella Infection (Chickenpox) in Pregnancy.第274号——妊娠期水痘感染(水痘)的管理
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