Cięszczyk Natalia, Czech Marcin, Pronicki Łukasz, Gujski Mariusz
Department of Public Health, Medical University of Warsaw, 02-091 Warszawa, Poland.
Institute of Mother and Child, 01-211 Warszawa, Poland.
Clin Pract. 2024 Jul 2;14(4):1285-1295. doi: 10.3390/clinpract14040104.
Clinical trials, by contributing to the development of diagnostics and to the search for modern, more effective, and safer therapies, have become one of the most important elements of the healthcare system. They enable the introduction of innovative drugs and treatments that can significantly improve patients' quality of life. Not only does this research help to understand disease mechanisms, but it also enables the personalization of therapy, which often increases the effectiveness of treatment. Public awareness of clinical trials helps build trust in science and medicine, which is fundamental to the effective functioning of the healthcare system. The aim of this study was to assess Poles' knowledge and beliefs about clinical trials.
The survey was conducted among Poles aged 18 and over with the help of an external company, Ariadna, which is an independent research panel. The questionnaire contained 22 questions, of which 13 questions concerned beliefs and attitudes towards clinical trials.
One thousand and seventy-nine participants took part in the study ( = 1079). The mean age of respondents was 44.96 years (SD = 16.30). Slightly more women ( = 568, 52.6%) than men ( = 511, 47.4%) took part in the study. Among the respondents, 86.5% ( = 933) were aware of clinical trials. The main sources of information about clinical trials were the media (53.8%) including the Internet ( = 355, 32.9%), TV ( = 175, 16.2%), press ( = 30, 2.8%), and radio ( = 21, 1.9%). 43.2% ( = 466) of respondents reported little knowledge of clinical trials, while more than three quarters ( = 805, 75.2%) said they would like to learn more about clinical trials. Most respondents ( = 879, 81.4%) agreed with the statement that participation in a clinical trial is completely voluntary, and more than half ( = 580, 53.7%) agreed with the statement that hospitals participating in clinical trials provide better healthcare. The statement that the results of clinical trials are made available to the public was disagreed with by 37.2% ( = 402) of participants. Only 30.3% ( = 327) of participants agreed that clinical trials should be conducted with children. Most respondents ( = 638, 59.1%) agreed with the statement that a patient in a clinical trial is insured. 48.3% ( = 521) of participants are aware that a clinical trial can be withdrawn from at any time.
Poles rate their knowledge of clinical trials as low and would like to learn more. Poles' knowledge of clinical trials is mainly based on commercial sources.
临床试验通过推动诊断技术的发展以及寻找现代、更有效且更安全的治疗方法，已成为医疗保健系统最重要的要素之一。它们使创新药物和治疗方法得以引入，显著改善患者的生活质量。这项研究不仅有助于理解疾病机制，还能实现治疗的个性化，这往往会提高治疗效果。公众对临床试验的认知有助于建立对科学和医学的信任，而这对医疗保健系统的有效运作至关重要。本研究的目的是评估波兰人对临床试验的了解和看法。
借助外部公司Ariadna（一个独立研究小组）对18岁及以上的波兰人进行了调查。问卷包含22个问题，其中13个问题涉及对临床试验的看法和态度。
1079名参与者参与了该研究。受访者的平均年龄为44.96岁（标准差 = 16.30）。参与研究的女性（568人，占52.6%）略多于男性（511人，占47.4%）。在受访者中，86.5%（933人）知晓临床试验。关于临床试验的主要信息来源是媒体（53.8%），包括互联网（355人，占32.9%）、电视（175人，占16.2%）、报纸（30人，占2.8%）和广播（21人，占1.9%）。43.2%（466人）的受访者表示对临床试验了解甚少，而超过四分之三（805人，占75.2%）的人表示希望更多地了解临床试验。大多数受访者（879人，占81.4%）同意参与临床试验完全是自愿的这一说法，超过一半（580人，占53.7%）的人同意参与临床试验的医院提供更好的医疗保健这一说法。37.2%（402人）的参与者不同意临床试验结果会向公众公开这一说法。只有30.3%（327人）的参与者同意应该对儿童进行临床试验。大多数受访者（638人，占59.1%）同意临床试验中的患者有保险这一说法。48.3%（521人）的参与者知道临床试验可以随时退出。
波兰人认为他们对临床试验的了解程度较低，并希望了解更多。波兰人对临床试验的了解主要基于商业来源。
