Guo Dongjie, Zou Meili, Fan Hongying, Yang Weiran, Zheng Jing
School of Chemistry and Chemical Engineering, Nanchang University, 999 XueFu Road, Nangchang 330031, China.
J Org Chem. 2024 Aug 16;89(16):11408-11413. doi: 10.1021/acs.joc.4c01083. Epub 2024 Jul 25.
A versatile method for the synthesis of cyclic trithiocarbonates has been successfully developed from readily synthesized propargyl alcohols and easily accessible carbon disulfide (CS), where terminal and nonterminal propargyl alkynols are compatible with this methodology. The developed protocol features simple, mild, atom-economic, and transition-metal-free reaction conditions resulting in the corresponding cyclic trithiocarbonates in moderate to excellent yields.
一种通用的环状三硫代碳酸酯合成方法已成功从易于合成的炔丙醇和易于获取的二硫化碳（CS₂）开发出来，其中末端和非末端炔丙醇都适用于该方法。所开发的方案具有简单、温和、原子经济且无过渡金属的反应条件，能以中等到优异的产率得到相应的环状三硫代碳酸酯。
