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住院患者糖尿病管理。

Inpatient diabetes management.

机构信息

Division of Endocrinology, Diabetes, and Metabolism, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Division of Hospital Medicine, Johns Hopkins Community Physicians, Johns Hopkins Medicine, Baltimore, Maryland, USA.

出版信息

Ann N Y Acad Sci. 2024 Aug;1538(1):5-20. doi: 10.1111/nyas.15190. Epub 2024 Jul 25.

Abstract

Diabetes mellitus is currently approaching epidemic proportions and disproportionately affects patients in the hospital setting. In the United States, individuals living with diabetes represent over 17 million emergency department visits and 8 million admissions annually. The management of these patients in the hospital setting is complex and differs considerably from the outpatient setting. All patients with hyperglycemia should be screened for diabetes, as in-hospital hyperglycemia portends a greater risk for morbidity, mortality, admission to an intensive care unit, and increased hospital length of stay. However, the definition of hyperglycemia, glycemic targets, and strategies to manage hyperglycemia in the inpatient setting can vary greatly depending on the population considered. Moreover, the presenting illness, changing nutritional status, and concurrent hospital medications often necessitate thoughtful consideration to adjustments of home diabetes regimens and/or the initiation of new insulin doses. This review article will examine core concepts and emerging new literature surrounding inpatient diabetes management, including glycemic targets, insulin dosing strategies, noninsulin medications, new diabetes technologies, inpatient diabetes management teams, and discharge planning strategies, to optimize patient safety and satisfaction, clinical outcomes, and even hospital financial health.

摘要

糖尿病目前正呈流行趋势,不成比例地影响着医院环境中的患者。在美国,患有糖尿病的个体每年代表着超过 1700 万次急诊就诊和 800 万次住院治疗。这些患者在医院环境中的管理非常复杂,与门诊环境有很大不同。所有高血糖患者都应筛查糖尿病,因为院内高血糖预示着发病率、死亡率、入住重症监护病房和住院时间延长的风险增加。然而,根据所考虑的人群,高血糖的定义、血糖目标以及管理住院患者高血糖的策略可能有很大差异。此外,当前的疾病、营养状况的变化以及同时使用的医院药物通常需要仔细考虑调整家庭糖尿病治疗方案和/或开始新的胰岛素剂量。这篇综述文章将探讨围绕住院患者糖尿病管理的核心概念和新出现的文献,包括血糖目标、胰岛素给药策略、非胰岛素药物、新的糖尿病技术、住院患者糖尿病管理团队以及出院计划策略,以优化患者的安全和满意度、临床结果甚至医院的财务健康。

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