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上颌窦底提升同期应用自体骨与复合骨移植后影像学植骨变化:一项为期一年的单盲随机对照研究。

Radiographic graft changes following maxillary sinus floor augmentation with autogenous bone compared with composite grafts: a one-year single-blind randomized controlled trial.

机构信息

Department of Oral and Maxillofacial Surgery, Aalborg University Hospital and Department of Clinical Medicine, Faculty of Medicine, Aalborg University, Aalborg, Denmark.

Department of Oral and Maxillofacial Surgery and Oral Medicine, Faculty of Odontology, Malmö University, Malmö, Sweden.

出版信息

Int J Oral Maxillofac Surg. 2024 Nov;53(11):968-980. doi: 10.1016/j.ijom.2024.07.010. Epub 2024 Jul 25.

Abstract

This study evaluated radiographic graft changes following maxillary sinus floor augmentation with (A) autogenous bone, (B) 1:1 autogenous bone and deproteinized porcine bone mineral, or (C) 1:1 autogenous bone and biphasic bone graft material. Sixty patients were randomly allocated to groups A, B, and C (20 in each). CBCT scans were obtained at enrolment, after surgery (T1), after prosthetic rehabilitation (T2), and 1 year after implant loading (T3). Significant decreases in graft volume (3D) and graft height (2D) from T1 to T3 were observed in all groups (P < 0.05). However, at T2 and T3, graft volume was significantly higher in group B than in groups A and C (P < 0.05), and graft height was significantly higher in group B than in group A (P < 0.05). Bone density increased significantly from T1 to T2 in all groups (P < 0.001). However, bone density was significantly higher in group B than in groups A and C, at T2 and T3 (P < 0.05). No significant correlation between graft volume or height and implant protrusion length or residual bone height was found. In conclusion, 1:1 autogenous bone and porcine bone resulted in significantly higher graft volume, height, and bone density when compared with autogenous bone or a 1:1 ratio of autogenous bone and biphasic bone. However the higher graft volume, height, and bone density did not appear to lead to improved outcomes at 1 year of functional loading when compared to the other groups.

摘要

本研究评估了上颌窦底提升后(A)自体骨、(B)1:1 自体骨和脱蛋白猪骨矿物质或(C)1:1 自体骨和双相骨移植物的影像学植骨变化。60 名患者随机分为 A、B 和 C 组(每组 20 名)。在入组时、手术后(T1)、修复体植入后(T2)和种植体负荷 1 年后(T3)获得 CBCT 扫描。所有组在 T1 至 T3 时均观察到骨移植体积(3D)和骨移植高度(2D)显著下降(P<0.05)。然而,在 T2 和 T3 时,B 组的骨移植体积明显高于 A 组和 C 组(P<0.05),B 组的骨移植高度明显高于 A 组(P<0.05)。所有组的骨密度从 T1 到 T2 均显著增加(P<0.001)。然而,在 T2 和 T3 时,B 组的骨密度明显高于 A 组和 C 组(P<0.05)。未发现骨移植体积或高度与种植体突出长度或剩余骨高度之间存在显著相关性。结论:与自体骨或 1:1 比例的自体骨和双相骨相比,1:1 自体骨和猪骨可显著增加骨移植体积、高度和骨密度。然而,与其他组相比,在 1 年功能负荷时,较高的骨移植体积、高度和骨密度似乎并未导致更好的结果。

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