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社会经济弱势社区中阿片类药物和加巴喷丁类药物减药的现实情况:一项定性评估

Realities of opioid and gabapentinoid deprescribing in socioeconomically disadvantaged communities: a qualitative evaluation.

作者信息

Parbery-Clark Charlotte L, Portice Jennie Sofia, Sowden Sarah

机构信息

Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK

Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK.

出版信息

BJGP Open. 2025 Apr 24;9(1). doi: 10.3399/BJGPO.2024.0160. Print 2025 Apr.

DOI:10.3399/BJGPO.2024.0160
PMID:39054299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12138019/
Abstract

BACKGROUND

Opioid and gabapentinoid prescribing has increased substantially in recent years despite having limited effectiveness in treating chronic primary pain. This is concerning, with the prescribing rates and adverse effects of these medications being higher in more socioeconomically disadvantaged groups. Guidance for prescribing and deprescribing these medications exists but the understanding of how deprescribing is operationalised, especially in areas of socioeconomic disadvantage, is limited.

AIM

To explore primary healthcare professionals' views and experiences of designing and implementing an intervention to reduce opioid and gabapentinoid prescribing.

DESIGN & SETTING: A qualitative evaluation, using participant observation and semi-structured interviews with primary healthcare professionals, working in practices serving areas of substantial socioeconomic disadvantage in the North East of England.

METHOD

Interviewees were purposively recruited with subsequent snowballing with participant observation of the peer-support meetings. Interview transcripts and notes from the participant observation were inductively coded and thematically analysed.

RESULT

Thirteen healthcare professionals from five practices were interviewed. Person-centred care with shared decision-making was strived for, which was time-consuming owing to the complexity of the problem and patients. Where shared decision-making was not possible, owing to patient refusal or non-engagement, risk was used to determine the appropriate action. This work involved an emotional toll on staff and patients, but was at times conversely easier and more rewarding than expected. Ultimately, demedicalising pain with a culture change is required to ensure patients are not prescribed these medications for inappropriate reasons or doses.

CONCLUSION

This study demonstrates key operational aspects to consider when undertaking opioid and gabapentinoid deprescribing in primary care, such as funding dedicated time to enable deprescribing.

摘要

背景

尽管阿片类药物和加巴喷丁类药物在治疗慢性原发性疼痛方面效果有限,但近年来其处方量仍大幅增加。这令人担忧,因为在社会经济地位较低的群体中,这些药物的处方率和不良反应更高。虽然存在关于这些药物处方和减药的指导意见,但对于如何实施减药,尤其是在社会经济不利地区,了解有限。

目的

探讨初级医疗保健专业人员对设计和实施减少阿片类药物和加巴喷丁类药物处方干预措施的看法和经验。

设计与背景

一项定性评估,采用参与观察法,并对在英格兰东北部社会经济状况严重不利地区工作的初级医疗保健专业人员进行半结构化访谈。

方法

通过目的抽样招募受访者,随后通过参与观察同伴支持会议进行滚雪球抽样。对访谈记录和参与观察笔记进行归纳编码和主题分析。

结果

来自五个医疗机构的13名医疗保健专业人员接受了访谈。努力实现以患者为中心的共同决策护理,但由于问题和患者的复杂性,这一过程耗时较长。当由于患者拒绝或不参与而无法进行共同决策时,则使用风险来确定适当的行动。这项工作给工作人员和患者带来了情感上的负担,但有时反而比预期的更容易且更有意义。最终,需要通过文化变革使疼痛非医学化,以确保患者不会因不适当的原因或剂量而被开具这些药物。

结论

本研究展示了在初级保健中进行阿片类药物和加巴喷丁类药物减药时需要考虑的关键操作方面,例如为减药投入专门时间的资金。

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本文引用的文献

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CDC Clinical Practice Guideline for Prescribing Opioids for Pain - United States, 2022.美国疾病预防控制中心 2022 年《疼痛阿片类药物处方临床实践指南》。
MMWR Recomm Rep. 2022 Nov 4;71(3):1-95. doi: 10.15585/mmwr.rr7103a1.
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Levelling up health: A practical, evidence-based framework for reducing health inequalities.提升健康水平:一个基于证据的减少健康不平等的实用框架。
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Opioid deprescribing: Qualitative perspectives from those with chronic non-cancer pain.阿片类药物减用:慢性非癌痛患者的定性观点。
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Br J Gen Pract. 2021 Sep 30;71(711):e788-e796. doi: 10.3399/BJGP.2020.1117. Print 2021 Oct.
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Br J Clin Pharmacol. 2021 Oct;87(10):4001-4012. doi: 10.1111/bcp.14827. Epub 2021 May 3.
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Challenges of opioid deprescribing and factors to be considered in the development of opioid deprescribing guidelines: a qualitative analysis.阿片类药物减用的挑战和制定阿片类药物减用指南时需要考虑的因素:定性分析。
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Building healthcare provider relationships for patient-centered care: A qualitative study of the experiences of people receiving injectable opioid agonist treatment.建立以患者为中心的医疗服务提供者关系:接受注射类阿片激动剂治疗者的经验定性研究。
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