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阿片类药物减用:慢性非癌痛患者的定性观点。

Opioid deprescribing: Qualitative perspectives from those with chronic non-cancer pain.

机构信息

Institute for Musculoskeletal Health, Sydney, Australia; Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Australia.

School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Australia.

出版信息

Res Social Adm Pharm. 2022 Dec;18(12):4083-4091. doi: 10.1016/j.sapharm.2022.07.043. Epub 2022 Aug 5.

Abstract

AIM

Deprescribing is the systematic process of discontinuing medications when the harms outweigh the benefits. This study aimed to identify barriers and facilitators in people with chronic non-cancer pain when deprescribing opioid analgesics, and their views on resources that assist with deprescribing.

METHODS

A purposive sampling strategy was used to recruit 19 adults with chronic non-cancer pain from the community who were, or had been, on long-term opioid therapy. Recruitment continued until thematic saturation was achieved. Semi-structured telephone interviews were conducted. A five-step framework and thematic analysis method identified themes for each study aim.

RESULTS

Themes identifying barriers to opioid deprescribing raised challenges of a lack of available alternatives, managing opioid dependency and withdrawal symptoms or inability to function without opioids when in extreme pain. Facilitating themes described the value of support networks, including a trusting doctor-patient relationship and finding individual coping strategies to address deprescribing barriers. We explored a variety of resources from electronic forms such as websites and apps to paper-based or face to face. Participants expressed that whatever the form, resources need to be educational but also simple and engaging.

CONCLUSIONS

Most people suffering from chronic non-cancer pain expressed dissatisfaction with being on opioids but most were still unwilling to deprescribe due to insufficient alternatives, a lack of support from their doctors and lack of information about the deprescribing process. Deprescribing can be facilitated by improving supportive networks and strategies and providing simple and positive educational resources.

摘要

目的

减药是指当药物的益处小于其危害时,系统地停止用药的过程。本研究旨在确定慢性非癌性疼痛患者在停用阿片类镇痛药时的障碍和促进因素,以及他们对有助于减药的资源的看法。

方法

采用目的抽样策略,从社区招募了 19 名患有慢性非癌性疼痛且正在或曾经接受长期阿片类药物治疗的成年人。继续招募,直到达到主题饱和。采用半结构化电话访谈进行。采用五步框架和主题分析方法,确定了每个研究目的的主题。

结果

识别阿片类药物减药障碍的主题提出了缺乏可用替代品、管理阿片类药物依赖和戒断症状或在极度疼痛时无法无药生存的挑战。促进主题描述了支持网络的价值,包括信任的医患关系和寻找个人应对策略来解决减药障碍。我们探讨了各种资源,从网站和应用程序等电子表格到纸质或面对面的资源。参与者表示,无论形式如何,资源都需要具有教育性,但也需要简单和吸引人。

结论

大多数患有慢性非癌性疼痛的人对服用阿片类药物表示不满,但由于替代品不足、医生支持不足以及对减药过程缺乏信息,大多数人仍不愿减药。通过改善支持网络和策略,并提供简单而积极的教育资源,可以促进减药。

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