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佐治亚州与妊娠相关的孕产妇死亡:死亡时间和原因。

Pregnancy-related maternal mortality in the state of Georgia: Timing and causes of death.

机构信息

Department of Community Medicine, Mercer University School of Medicine, Savannah, GA, USA.

Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.

出版信息

Womens Health (Lond). 2024 Jan-Dec;20:17455057241267103. doi: 10.1177/17455057241267103.

Abstract

BACKGROUND

The maternal mortality rate in the United States is high and disparities among non-Hispanic White and non-Hispanic Black women remain. In the State of Georgia, the pregnancy-related death rate is among the worst in the nation.

OBJECTIVE

To examine current pregnancy-related deaths in the State of Georgia using measures of timing and cause-specific mortality across maternal sociodemographic characteristics.

DESIGN

This cross-sectional study of pregnancy-related deaths in Georgia was based on 2016-2019 maternal mortality data obtained from the Georgia Department of Public Health.

METHODS

Our study analysis involved complete-case data of maternal deaths identified as pregnancy-related deaths ( = 129). Statistical analyses included two distinct population-level measures: (a) timing (i.e. during pregnancy, 0 to 60 days, 61 to 180 days, and 181 to 365 days postpartum) and (b) cause-specific deaths patterned by sociodemographic groups of women and by rural and urban county of residence. Categorical variables were compared using the Chi square or Fisher's exact test and presented as numbers and percentages. A power analysis was conducted to inform whether there was sufficient power to detect statistically significant effects given available sample sizes.

RESULTS

Among a total of 129 pregnancy-related deaths, 30 (23.3%) deaths occurred during pregnancy and 63 (48.8%) deaths occurred within the first 60 days postpartum. Pregnancy-related deaths were disproportionally common among non-Hispanic Black, 25 to 34 years old, and poorly educated women. Three leading underlying causes, cardiomyopathy (22.7%), hemorrhage (21.6%), and cardiovascular or coronary disease (20.4%), accounted for about 65% of all pregnancy-related deaths. Mental health conditions were common causes of death among non-Hispanic White women during pregnancy and in late postpartum.

CONCLUSION

Continued monitoring, collecting and analyzing reliable data will help identify root causes and find ways to eliminate the disproportionate burden of pregnancy-related deaths in the State of Georgia.

摘要

背景

美国的孕产妇死亡率较高,非西班牙裔白人和非西班牙裔黑人群体之间仍然存在差异。在佐治亚州,与妊娠相关的死亡率位居全美最差之列。

目的

通过分析孕产妇社会人口学特征与妊娠相关死亡的时间和病因特异性死亡率,来研究佐治亚州当前的妊娠相关死亡情况。

设计

本研究基于佐治亚州公共卫生部在 2016 年至 2019 年期间获取的孕产妇死亡率数据,对佐治亚州的妊娠相关死亡进行了横断面研究。

方法

本研究分析了 129 例被确定为妊娠相关死亡的孕产妇死亡完整病例数据。统计分析包括两个不同的人群水平指标:(a)时间(即妊娠期间、产后 0 至 60 天、61 至 180 天和 181 至 365 天)和(b)按妇女社会人口学群体以及农村和城市县居住地模式划分的病因特异性死亡。使用卡方检验或 Fisher 确切检验比较分类变量,并以数字和百分比表示。进行了功效分析,以确定根据现有样本量是否有足够的功效来检测具有统计学意义的效果。

结果

在总共 129 例妊娠相关死亡中,有 30 例(23.3%)发生在妊娠期间,有 63 例(48.8%)发生在产后 60 天内。非西班牙裔黑人、25 至 34 岁和受教育程度低的妇女妊娠相关死亡的比例过高。导致妊娠相关死亡的三个主要潜在病因分别为心肌病(22.7%)、出血(21.6%)和心血管或冠状动脉疾病(20.4%),约占所有妊娠相关死亡的 65%。精神健康状况是非西班牙裔白人妇女在妊娠期间和产后晚期死亡的常见原因。

结论

继续监测、收集和分析可靠的数据将有助于确定根本原因,并找到消除佐治亚州妊娠相关死亡比例过高的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ebb/11282520/8369c4e69598/10.1177_17455057241267103-fig1.jpg

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