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放射性致脱毛与介入神经放射学程序的相关性。

Association of radiation-induced epilation and interventional neuroradiology procedures.

机构信息

Biomedical Technology Services, Gold Coast University Hospital, Southport, Queensland, Australia.

Department of Interventional Neuroradiology, Gold Coast University Hospital, Southport, Queensland, Australia.

出版信息

J Med Imaging Radiat Oncol. 2024 Oct;68(7):787-795. doi: 10.1111/1754-9485.13730. Epub 2024 Jul 26.

DOI:10.1111/1754-9485.13730
PMID:39054930
Abstract

INTRODUCTION

The aim of this study is to quantify the association of temporary epilation following interventional neuroradiology (INR) procedures and compare the peak skin dose (D) threshold to published values.

METHODS

Gold Coast University Hospital (GCUH) is a major centre for INR with over 500 primarily interventional procedures performed every year. D is calculated when the reference air kerma (K) exceeds 3 Gy. If the D exceeds 3 Gy, the patient is followed up for any skin effects. An audit was undertaken of these results over a 2-year period.

RESULTS

From January 2020 to December 2021, 140 patients who underwent INR procedures had a K > 3 Gy, 66 resulted in a calculated D >3 Gy, and 45 were successfully followed up. Twenty patients (44%) reported no skin effects and 25 (56%) reported skin effects, which were almost exclusively epilation. The mean (range) D for patients with no reported skin effects and those with observed skin effects was 4.6 Gy (3.0-11.1 Gy) and 4.2 Gy (3.0-7.0 Gy), respectively.

CONCLUSION

These results demonstrate that temporary epilation was observed in 56% of patients, in a cohort of 45 patients who underwent an INR procedure with calculated D >3 Gy and successful follow-up. The results support evidence in the literature that suggests the approximate threshold for temporary epilation reported by the International Commission on Radiological Protection (ICRP) may be too high for incidence of this effect, specifically on the scalp, when D is calculated from K (using commonly used corrections and assumptions in the calculation).

摘要

简介

本研究旨在量化介入神经放射学(INR)术后临时脱毛的相关性,并比较发表的峰值皮肤剂量(D)阈值。

方法

黄金海岸大学医院(GCUH)是 INR 的主要中心,每年进行超过 500 次主要介入性手术。当参考空气比释动能(K)超过 3Gy 时,计算 D。如果 D 超过 3Gy,则对患者进行任何皮肤影响的随访。在两年期间对这些结果进行了审核。

结果

2020 年 1 月至 2021 年 12 月,140 名接受 INR 手术的患者 K>3Gy,66 名患者计算的 D>3Gy,45 名患者成功随访。20 名患者(44%)报告无皮肤影响,25 名患者(56%)报告皮肤影响,几乎完全是脱毛。无报告皮肤影响和观察到皮肤影响的患者的平均(范围)D 分别为 4.6Gy(3.0-11.1Gy)和 4.2Gy(3.0-7.0Gy)。

结论

这些结果表明,在 45 名接受 INR 手术且计算的 D>3Gy 并成功随访的患者中,56%的患者出现了暂时性脱毛。结果支持文献中的证据,表明国际辐射防护委员会(ICRP)报告的暂时性脱毛的近似阈值对于头皮上这种效应的发生率可能过高,特别是当使用常用的计算中校正和假设从 K 计算 D 时。

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