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石榴皮粉强化全谷物薄饼对糖尿病预防的作用:一项随机临床试验。

Effect of pomegranate peel powder-infused multigrain chapatti on diabetes prevention: A randomized clinical trial.

作者信息

Zubair Muhammad, Ahmed Aftab, Afzaal Muhammad, Saeed Farhan, Faisal Zargham, Asghar Aasma, Akram Noor, Manoharadas Salim, Nawaz Asad, Asres Degnet Teferi

机构信息

Department of Food and Nutrition Government College University Faisalabad Faisalabad Pakistan.

Department of Nutritional Sciences Government College University Faisalabad Faisalabad Pakistan.

出版信息

Food Sci Nutr. 2024 Apr 12;12(7):4879-4892. doi: 10.1002/fsn3.4134. eCollection 2024 Jul.

Abstract

Diabetes mellitus is a metabolic and chronic disease linked to lifestyle factors like dietary patterns and physical inactivity. This randomized clinical study aimed to develop a novel dietary intervention using pomegranate peel powder-based multigrain chapatti to prevent diabetes. The product was formulated by incorporating pomegranate peel powder into a mixture of wheat flour, pearl flour, millet flour, and chickpea flour. The study included the formulation of various treatments (T, T, T, and T) following product development, and these treatments were subjected to comprehensive assessments. The nutritional composition and antioxidant potential of the pomegranate peel powder-based multigrain chapatti were analyzed. Sensory attributes, including taste, texture, and overall acceptability, were evaluated. Additionally, biochemical analyses, including blood glucose levels and HbA1C, were conducted to assess the impact of the interventions on blood glucose metabolism. The results revealed that the nutritional profile and phytochemical potential of the product improved significantly in treatment T, which contained 15% pomegranate juice. Overall acceptability was found to be high for T, indicating that the inclusion of pomegranate peel powder was well received in terms of taste and sensory qualities. Importantly, the clinical trial demonstrated positive outcomes in the intervention group receiving the pomegranate peel powder-based multigrain chapatti. Blood glucose analysis and HbA1C assessments indicated that the consumption of this innovative dietary product contributed to improved blood glucose metabolism, suggesting its potential as a preventive strategy for diabetes.

摘要

糖尿病是一种与饮食模式和缺乏身体活动等生活方式因素相关的代谢性慢性疾病。这项随机临床研究旨在开发一种以石榴皮粉为基础的多谷物薄饼的新型饮食干预措施来预防糖尿病。该产品是通过将石榴皮粉加入小麦粉、珍珠粉、小米粉和鹰嘴豆粉的混合物中配制而成。该研究包括在产品开发后制定各种处理方式(T1、T2、T3和T4),并对这些处理方式进行全面评估。分析了以石榴皮粉为基础的多谷物薄饼的营养成分和抗氧化潜力。评估了包括味道、质地和总体可接受性在内的感官特性。此外,还进行了包括血糖水平和糖化血红蛋白在内的生化分析,以评估这些干预措施对血糖代谢的影响。结果显示,在含有15%石榴汁的T2处理中,该产品的营养成分和植物化学潜力有显著改善。发现T2的总体可接受性较高,这表明就味道和感官品质而言,石榴皮粉的加入很受欢迎。重要的是,临床试验表明,接受以石榴皮粉为基础的多谷物薄饼的干预组取得了积极成果。血糖分析和糖化血红蛋白评估表明,食用这种创新型饮食产品有助于改善血糖代谢,表明其作为糖尿病预防策略的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/539a/11266937/73cd4a21ce41/FSN3-12-4879-g002.jpg

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