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孕期均衡能量蛋白质补充:埃塞俄比亚农村孕妇的依从性和可接受性

Balanced Energy Protein Supplementation in Pregnancy: Adherence and Acceptability among Pregnant Women in Rural Ethiopia.

作者信息

Eglovitch Michelle, Abate Firehiwot Workneh, Shifraw Tigest, Shiferie Fisseha, Amanuel Hanna, Tadesse Amare Worku, Worku Alemayehu, Isanaka Sheila, Berhane Yemane, Lee Anne Cc

机构信息

Brigham and Women's Hospital, Boston, MA, United States.

Virginia Commonwealth University, Richmond, VA, United States.

出版信息

Curr Dev Nutr. 2024 Jun 13;8(7):103796. doi: 10.1016/j.cdnut.2024.103796. eCollection 2024 Jul.

DOI:10.1016/j.cdnut.2024.103796
PMID:39055242
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11269774/
Abstract

BACKGROUND

Balanced energy protein (BEP) supplementation in pregnant women in low-and middle-income countries may reduce the risk of stillbirth and low birth weight.

OBJECTIVES

The objective of this study was to assess the adherence to and acceptability of a corn-soy blend (CSB) BEP product among pregnant women in rural Ethiopia.

METHODS

This formative study was conducted from October to November 2018 among pregnant women in the rural Amhara region of Ethiopia prior to initiation of a clinical effectiveness study (ISRCTN: 15116516). We assessed adherence and acceptability of a micronutrient-fortified CSB BEP supplement among 40 pregnant women during a 4-wk utilization period. Acceptability was assessed using a 7-point Likert-style scale about the hedonic characteristics of the BEP product at 2 wk and 4 wk. Adherence was assessed by weekly monitoring and empty sachet counts for BEP consumption over 4 wk.

RESULTS

Adherence to the BEP was, on average, 89% over the month-long pilot. The BEP product was rated favorably (mean Likert score >6 of 7) for the following domains: color, taste, odor, and likeability at mid and endpoints. Women found the product convenient to eat [mean (standard deviation [SD] = 5.9 (1.0))] and filling (mean (SD) = 6.1 (1.5) out of 7). Scores on acceptability and perception of the product remained stable throughout the duration of use. A majority of women (63%) reported consuming the BEP as a snack to supplement meals and splitting the serving over 2 or more sessions (68%). A quarter of respondents reported sharing the supplement with family members.

CONCLUSIONS

Adherence and acceptability of the CSB BEP product were high among this population in rural Amhara, Ethiopia. This formative data was important to select the final product and shape the counseling and delivery of BEP in the parent study.

摘要

背景

在低收入和中等收入国家,孕妇补充能量蛋白质平衡剂(BEP)可能会降低死产和低出生体重的风险。

目的

本研究的目的是评估埃塞俄比亚农村地区孕妇对玉米-大豆混合粉(CSB)BEP产品的依从性和可接受性。

方法

这项形成性研究于2018年10月至11月在埃塞俄比亚阿姆哈拉农村地区的孕妇中进行,先于一项临床有效性研究(国际标准随机对照试验编号:15116516)开展。在为期4周的使用期内,我们评估了40名孕妇对一种强化微量营养素的CSB BEP补充剂的依从性和可接受性。在第2周和第4周,使用7点李克特量表评估BEP产品享乐特性方面的可接受性。通过每周监测和4周内BEP食用空袋计数评估依从性。

结果

在为期一个月的试点期间,对BEP的平均依从率为89%。BEP产品在以下方面获得好评(李克特平均得分>7分中的6分):中期和末期的颜色、味道、气味和喜爱度。女性认为该产品食用方便(平均(标准差[SD])=5.9(1.0))且有饱腹感(7分制下平均(SD)=6.1(1.5))。在整个使用期间,产品可接受性和认知度得分保持稳定。大多数女性(63%)报告将BEP作为零食补充膳食,并分2次或更多次食用(68%)。四分之一的受访者报告与家庭成员分享补充剂。

结论

在埃塞俄比亚阿姆哈拉农村地区的这一人群中,CSB BEP产品的依从性和可接受性较高。这些形成性数据对于选择最终产品以及在母研究中指导BEP的咨询和发放非常重要。

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Curr Dev Nutr. 2023 Apr 17;7(6):100079. doi: 10.1016/j.cdnut.2023.100079. eCollection 2023 Jun.
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Small babies, big risks: global estimates of prevalence and mortality for vulnerable newborns to accelerate change and improve counting.小婴儿,大风险:脆弱新生儿的全球患病率和死亡率估计数,以加速变革和改善计数。
Lancet. 2023 May 20;401(10389):1707-1719. doi: 10.1016/S0140-6736(23)00522-6. Epub 2023 May 8.
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Harmonization of maternal balanced energy-protein supplementation studies for individual participant data (IPD) meta-analyses - finding and creating similarities in variables and data collection.对个体参与者数据 (IPD) 荟萃分析进行孕产妇均衡能量-蛋白质补充研究的协调——在变量和数据收集方面寻找和创造相似性。
BMC Pregnancy Childbirth. 2023 Feb 11;23(1):107. doi: 10.1186/s12884-023-05366-2.
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Enhancing Nutrition and Antenatal Infection Treatment (ENAT) study: protocol of a pragmatic clinical effectiveness study to improve birth outcomes in Ethiopia.增强营养和产前感染治疗(ENAT)研究:一项旨在改善埃塞俄比亚分娩结局的实用临床效果研究方案。
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