Alavidze Irakli, Shubitidze Mariam, Khodeli Gvantsa, Dvali Shorena, Tskitishvili Aleksandre
Aieti Medical School, David Tvildiani Medical University, Tbilisi, GEO.
School of Medicine, Ilia State University, Tbilisi, GEO.
Cureus. 2024 Jun 25;16(6):e63090. doi: 10.7759/cureus.63090. eCollection 2024 Jun.
Tuberculosis (TB) is still one of the most challenging infectious diseases worldwide. Coinfection with HIV increases the likelihood of extrapulmonary involvement, including the tuberculosis of the central nervous system (CNS-TB). CNS-TB often presents as tuberculomas or tuberculous meningitis. Although tuberculomas can be single or multiple, asymptomatic carriage of numerous tuberculomas is seldom reported. We present a case of a 55-year-old man who carried at least 34 tuberculomas of different sizes asymptomatically before developing and succumbing to tuberculous meningitis. Furthermore, we highlight several possible public health challenges that might have complicated his clinical course, suggesting that future studies also focus on these variables alongside more traditional clinical issues.
结核病(TB)仍然是全球最具挑战性的传染病之一。与艾滋病毒合并感染会增加肺外受累的可能性,包括中枢神经系统结核病(CNS-TB)。CNS-TB通常表现为结核瘤或结核性脑膜炎。虽然结核瘤可以是单个或多个,但很少有关于大量结核瘤无症状携带的报道。我们报告一例55岁男性病例,该患者在发生并死于结核性脑膜炎之前,无症状地携带了至少34个大小不同的结核瘤。此外,我们强调了几个可能使他的临床病程复杂化的公共卫生挑战,表明未来的研究除了关注更传统的临床问题外,也应关注这些变量。