Mazloom Mahdi, Heravian Shandiz Javad, Jafarzadeh Sadegh, Jamali Jamshid, Momeni-Moghaddam Hamed
Department of Optometry, School of Paramedical and Rehabilitation Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
Refractive Errors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
J Ophthalmic Vis Res. 2024 Jun 21;19(2):219-226. doi: 10.18502/jovr.v19i2.10910. eCollection 2024 Apr-Jun.
The possible effects of refractive errors on vestibulo-ocular reflex (VOR) has been a conflicting issue. The aim of this study was to evaluate the effects of induced myopia on VOR using the ocular Vestibular Evoked Myogenic Potential (oVEMP).
In this cross-sectional quasi-experimental study, 35 emmetropic and normal subjects with the mean age of 23.89 3.93 (range, 20-40 years) without any ocular, nervous system, and vestibular disorders, underwent the oVEMP test in the comprehensive rehabilitation center of Mashhad University of Medical Sciences. The oVEMP was performed under five different conditions of testing binocularly, monocularly, and when myopia was induced with the use of spherical lenses of +1.00, +3.00, and +5.00 diopters, respectively. There were 2 to 5 min of rest with closed eyes after each condition to avoid adaptation, fatigue, and any other sources of bias. Mean latencies of oVEMP waves (N1 and P1) and amplitudes of N1-P1 complex were measured.
There was no significant difference between the right and left sides ( 0.05). The induced myopia significantly increased the N1 and P1 latencies using lenses of +1.00, +3.00, and +5.00 diopters but the amplitudes of N1-P1 complex were not influenced by the different amounts of induced myopia. There was no significant difference among the different conditions of induced myopia either ( 0.05).
Induced myopia could affect the VOR due to prolonging the latencies of oVEMP waves. However, the amplitudes were not affected and the effects of multiple degrees of induced myopia were not significantly different.
屈光不正对前庭眼反射（VOR）的可能影响一直是个有争议的问题。本研究的目的是使用眼前庭诱发肌源性电位（oVEMP）评估诱导性近视对VOR的影响。
在这项横断面准实验研究中，35名平均年龄为23.89±3.93岁（范围20 - 40岁）的正视且正常的受试者，无任何眼部、神经系统和前庭疾病，在马什哈德医科大学综合康复中心接受oVEMP测试。oVEMP测试分别在双眼、单眼以及使用+1.00、+3.00和+5.00屈光度的球面透镜诱导近视这五种不同条件下进行。每种条件后闭眼休息2至5分钟，以避免适应、疲劳和任何其他偏差来源。测量oVEMP波（N1和P1）的平均潜伏期以及N1 - P1复合波的振幅。
左右两侧之间无显著差异（P>0.05）。使用+1.00、+3.00和+5.00屈光度的透镜诱导近视显著增加了N1和P1潜伏期，但N1 - P1复合波的振幅不受不同程度诱导近视的影响。不同程度诱导近视的条件之间也无显著差异（P>0.05）。
诱导性近视可通过延长oVEMP波的潜伏期影响VOR。然而，振幅不受影响，且不同程度诱导近视的影响无显著差异。
