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联合使用亮蓝和台盼蓝作为玻璃体视网膜手术的活性染料

Combined Brilliant and Trypan Blue As Vital Dyes for Chromovitrectomy.

作者信息

Ferreira Bruno Fortaleza de A, Sakuno Gustavo, Mika Kato Juliana, Bonatti Rodolfo, Ferreira Álvaro Fernandes, Nakashima Aloisio Fumio, Nakashima Yoshitaka

机构信息

Department of Ophthalmology, University of Sao Paulo, Sao Paulo, Brazil.

Department of Ophthalmology, Hospital Geral de Fortaleza, Ceará, Brazil.

出版信息

J Ophthalmic Vis Res. 2024 Jun 21;19(2):264-266. doi: 10.18502/jovr.v19i2.7652. eCollection 2024 Apr-Jun.

DOI:10.18502/jovr.v19i2.7652
PMID:39055514
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11267129/
Abstract

Brilliant blue 0.05% and trypan blue 0.1% were mixed in a proportion of 1:1 in a 1-mL syringe. This combination produced a waterfall effect with the fast sinking of the dye to the posterior pole and little diffusion through the vitreous cavity. Therefore, it can effectively stain the internal limiting membrane and the epiretinal membrane with a good contrast during surgeries for a macular hole, myopic foveoschisis, and macular pucker.

摘要

将0.05%的亮蓝和0.1%的台盼蓝以1:1的比例混合于1毫升注射器中。这种组合产生了一种瀑布效应,染料迅速下沉至后极,且在玻璃体腔中扩散极少。因此,在黄斑裂孔、近视性黄斑劈裂和黄斑皱褶手术中,它能有效染色内界膜和视网膜前膜,对比度良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62a0/11267129/c76bdeb61df4/jovr-19-264-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62a0/11267129/46aa207d5c82/jovr-19-264-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62a0/11267129/8cd950fa115a/jovr-19-264-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62a0/11267129/f8a48d8156bd/jovr-19-264-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62a0/11267129/c76bdeb61df4/jovr-19-264-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62a0/11267129/46aa207d5c82/jovr-19-264-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62a0/11267129/8cd950fa115a/jovr-19-264-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62a0/11267129/f8a48d8156bd/jovr-19-264-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62a0/11267129/c76bdeb61df4/jovr-19-264-g004.jpg

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本文引用的文献

1
The Combination of Trypan Blue and Brilliant Blue G-Assisted Vitrectomy for Macular Pucker: Histopathological Findings.锥虫蓝与亮蓝G联合辅助玻璃体切除术治疗黄斑皱襞:组织病理学研究结果
Ophthalmologica. 2018;239(2-3):167-175. doi: 10.1159/000485986. Epub 2018 Jan 25.
2
Chromovitrectomy and vital dyes.脉络膜视网膜玻璃体切除术与活性染料
Dev Ophthalmol. 2014;54:120-5. doi: 10.1159/000360457. Epub 2014 Aug 26.
3
Origins and consequences of hyperosmolar stress in retinal pigmented epithelial cells.视网膜色素上皮细胞中高渗应激的起源与后果
Front Physiol. 2014 May 30;5:199. doi: 10.3389/fphys.2014.00199. eCollection 2014.
4
Dyes for Eyes™: hydrodynamics, biocompatibility and efficacy of 'heavy' (dual) dyes for chromovitrectomy.用于眼内染色的染料:重(双)染料用于铬玻璃体切割术的流体动力学、生物相容性和疗效。
Ophthalmologica. 2013;230 Suppl 2:51-8. doi: 10.1159/000353870. Epub 2013 Sep 6.
5
Novel 'heavy' dyes for retinal membrane staining during macular surgery: multicenter clinical assessment.新型“重”染料在黄斑手术中用于视网膜膜染色:多中心临床评估。
Acta Ophthalmol. 2014 Jun;92(4):339-44. doi: 10.1111/aos.12208. Epub 2013 Jun 20.
6
Brilliant Blue G as protective agent against trypan blue toxicity in human retinal pigment epithelial cells in vitro.亮蓝 G 作为一种保护剂,防止体外人视网膜色素上皮细胞中锥虫蓝的毒性。
Graefes Arch Clin Exp Ophthalmol. 2013 Jul;251(7):1735-40. doi: 10.1007/s00417-013-2342-3. Epub 2013 Apr 14.
7
Comparative toxicology of trypan blue, brilliant blue G, and their combination together with polyethylene glycol on human pigment epithelial cells.三苯甲烷类染料(锥虫蓝、亮蓝 G)及其与聚乙二醇联合应用对人眼色素上皮细胞的比较毒理学研究
Invest Ophthalmol Vis Sci. 2011 Jun 9;52(7):4085-90. doi: 10.1167/iovs.10-6336.