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Parkinson-like neurotoxicity in female patients treated with idecabtagene-vicleucel.

作者信息

Couturier Audrey, Escoffre Martine, Leh Frédérique, Villoteau Anne-Sophie, Palard Xavier, Le Jeune Florence, Decaux Olivier, Lamy Thierry, Houot Roch

机构信息

Department of Hematology CHU de Rennes Rennes France.

Department of Neurology Rennes France.

出版信息

Hemasphere. 2024 Jul 25;8(7):e131. doi: 10.1002/hem3.131. eCollection 2024 Jul.

DOI:10.1002/hem3.131
PMID:39055647
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11270580/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c0d/11270580/cde16a5ab25a/HEM3-8-e131-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c0d/11270580/cde16a5ab25a/HEM3-8-e131-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c0d/11270580/cde16a5ab25a/HEM3-8-e131-g001.jpg

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本文引用的文献

1
Neurologic toxicities following adoptive immunotherapy with BCMA-directed CAR T cells.采用靶向BCMA的嵌合抗原受体T细胞进行过继性免疫治疗后的神经毒性。
Blood. 2023 Oct 5;142(14):1243-1248. doi: 10.1182/blood.2023020571.
2
Chemotherapy-induced reversal of ciltacabtagene autoleucel-associated movement and neurocognitive toxicity.化疗诱导的 cilta-cabtagene autoleucel 相关运动和神经认知毒性逆转。
Blood. 2023 Oct 5;142(14):1248-1252. doi: 10.1182/blood.2023021429.
3
Cilta-cel or Standard Care in Lenalidomide-Refractory Multiple Myeloma.
Blood Cancer J. 2024 Nov 26;14(1):206. doi: 10.1038/s41408-024-01191-8.
4
Case report: Treatment of parkinsonism secondary to ciltacabtagene autoleucel using a combination dopaminergic regimen.病例报告:使用多巴胺能药物联合方案治疗 cilta-cabtagene autoleucel 引起的帕金森病。
Front Immunol. 2024 Sep 20;15:1444010. doi: 10.3389/fimmu.2024.1444010. eCollection 2024.
西达基奥仑赛或标准护理用于来那度胺难治性多发性骨髓瘤。
N Engl J Med. 2023 Jul 27;389(4):335-347. doi: 10.1056/NEJMoa2303379. Epub 2023 Jun 5.
4
Ciltacabtagene Autoleucel, an Anti-B-cell Maturation Antigen Chimeric Antigen Receptor T-Cell Therapy, for Relapsed/Refractory Multiple Myeloma: CARTITUDE-1 2-Year Follow-Up.西达基奥仑赛,一种抗 B 细胞成熟抗原嵌合抗原受体 T 细胞疗法,用于治疗复发/难治性多发性骨髓瘤:CARTITUDE-1 研究 2 年随访结果。
J Clin Oncol. 2023 Feb 20;41(6):1265-1274. doi: 10.1200/JCO.22.00842. Epub 2022 Jun 4.
5
Incidence and management of CAR-T neurotoxicity in patients with multiple myeloma treated with ciltacabtagene autoleucel in CARTITUDE studies.CARTITUDE 研究中接受 cilta-celgene autoleucel 治疗的多发性骨髓瘤患者的 CAR-T 神经毒性的发生率和管理。
Blood Cancer J. 2022 Feb 24;12(2):32. doi: 10.1038/s41408-022-00629-1.
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Neurocognitive and hypokinetic movement disorder with features of parkinsonism after BCMA-targeting CAR-T cell therapy.BCMA 靶向 CAR-T 细胞治疗后出现以帕金森病为特征的神经认知和运动障碍。
Nat Med. 2021 Dec;27(12):2099-2103. doi: 10.1038/s41591-021-01564-7. Epub 2021 Dec 10.
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