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新冠病毒检测呈阳性患者中儿童和青年多系统炎症综合征(MIS-C)的流行病学研究——来自国家住院患者样本数据库的数据

An epidemiological study of multisystem inflammatory syndrome in children (MIS-C) and young adults among COVID-19-positive patients - data from National Inpatient Sample database.

作者信息

Aggarwal Shruti, Dhaliwal Jasninder Singh, Kumar Nomesh, Sakthivel Hemamalini, Ahmed Raheel, Verma Renuka, Ramphul Kamleshun

机构信息

Guru Gobind Singh Medical College, Sadiq Road, Faridkot, India.

Department of Internal Medicine, University of California, Riverside, United States.

出版信息

Reumatologia. 2024;62(3):214-216. doi: 10.5114/reum/189213. Epub 2024 Jun 7.

DOI:10.5114/reum/189213
PMID:39055727
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11267655/
Abstract

During the pandemic of COVID-19, a novel atypical set of clinical findings was seen among several children with recent or current exposure to the virus. It was termed the "multisystem inflammatory syndrome in children" (MIS-C). Our study used the 2021 National Inpatient Sample to study the associations of sex, race, and age with the incidence of MIS-C among COVID-19-positive children. Out of 69,440 COVID-19-positive children, 2,790 (4.0%) reported MIS-C. The incidence of MIS-C was highest among those aged 8 years old (17,130 MIS-C cases per 100,000 COVID-19 patients), Asian or Pacific Islanders (API) (5,346 MIS-C per 100,000 COVID-19 cases), and males (4,734 cases per 100,000 COVID-19 cases). Furthermore, 7.9% of MIS-C cases met the classification of Kawasaki disease.

摘要

在新冠疫情期间,在近期或当前接触过该病毒的几名儿童中发现了一组新的非典型临床症状。它被称为“儿童多系统炎症综合征”(MIS-C)。我们的研究使用了2021年全国住院患者样本,以研究性别、种族和年龄与新冠病毒检测呈阳性儿童中MIS-C发病率之间的关联。在69440名新冠病毒检测呈阳性的儿童中,2790名(4.0%)报告患有MIS-C。MIS-C的发病率在8岁儿童中最高(每10万名新冠患者中有17130例MIS-C病例),在亚裔或太平洋岛民(API)中最高(每10万例新冠病例中有5346例MIS-C),在男性中最高(每10万例新冠病例中有4734例)。此外,7.9%的MIS-C病例符合川崎病的分类。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8f6/11267655/afa6fbed00d3/RU-62-189213-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8f6/11267655/0d33adb3f52c/RU-62-189213-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8f6/11267655/0954e1d469d5/RU-62-189213-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8f6/11267655/afa6fbed00d3/RU-62-189213-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8f6/11267655/0d33adb3f52c/RU-62-189213-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8f6/11267655/0954e1d469d5/RU-62-189213-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8f6/11267655/afa6fbed00d3/RU-62-189213-g003.jpg

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Association of Ethnicity With Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2 Infection: An International Case-Referent Study.种族与儿童感染SARS-CoV-2相关的多系统炎症综合征的关联:一项国际病例对照研究。
Front Pediatr. 2021 Oct 15;9:707650. doi: 10.3389/fped.2021.707650. eCollection 2021.
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Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS): Prospective, national surveillance, United Kingdom and Ireland, 2020.
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