Marschner Felix, Kanzow Philipp, Wiegand Annette
Department of Preventive Dentistry, Periodontology and Cariology, University Medical Center Göttingen, Göttingen, Germany.
Int J Paediatr Dent. 2025 Mar;35(2):389-404. doi: 10.1111/ipd.13250. Epub 2024 Jul 26.
Erosive tooth wear is a multifactorial and common condition in children.
This systematic review and meta-analysis aimed to determine the prevalence and key risk factors for erosive tooth wear in the primary dentition of children up to 7 years of age.
Electronic databases (PubMed, Embase, Scopus, and Web of Science) were searched in February 2023 for observational studies reporting prevalence and anamnestic risk factors. Additionally, a manual hand search was performed. Meta-analyses were conducted for the prevalence and odds ratios of identified risk factors. Risk of bias was assessed using the Newcastle-Ottawa scale modified for cross-sectional studies.
A total of 26 sources, reporting on 23 studies, were included in the systematic review. The overall estimated prevalence of children with erosive tooth wear in the primary dentition amounted to 35.6% (95% CI: 24.8-48.1). Anamnestic factors were structured into domains. Meta-analyses revealed gastroesophageal reflux disease (GERD; p = .008; OR = 1.98, 95% CI: 1.37-2.87), consumption of acidic food (p < .001; OR = 5.14, 95% CI: 3.56-7.42) and acidic drinks (p < .001; OR = 6.90, 95% CI: 4.64-10.25), holding beverages in the mouth while drinking (p = .035; OR = 1.82, 95% CI: 1.26-2.63), and snacking regularly (p = .041; OR = 1.58, 95% CI: 1.18-2.10) to be significantly associated with erosive tooth wear.
Future research should use standardized questionnaires to assess erosive tooth wear and its underlying risk factors (PROSPERO: CRD4202339776).
侵蚀性牙齿磨损是儿童中一种多因素导致的常见病症。
本系统评价和荟萃分析旨在确定7岁及以下儿童乳牙列中侵蚀性牙齿磨损的患病率和主要风险因素。
于2023年2月检索电子数据库（PubMed、Embase、Scopus和Web of Science），以查找报告患病率和既往风险因素的观察性研究。此外，还进行了人工手工检索。对已识别风险因素的患病率和比值比进行荟萃分析。使用针对横断面研究修改后的纽卡斯尔-渥太华量表评估偏倚风险。
系统评价共纳入26个来源，报告了23项研究。乳牙列中患有侵蚀性牙齿磨损儿童的总体估计患病率为35.6%（95%置信区间：24.8 - 48.1）。既往因素按领域进行分类。荟萃分析显示，胃食管反流病（GERD；p = 0.008；比值比 = 1.98，95%置信区间：1.37 - 2.87）、食用酸性食物（p < 0.001；比值比 = 5.14，95%置信区间：3.56 - 7.42）和酸性饮料（p < 0.001；比值比 = 6.90，95%置信区间：4.64 - 10.25）、饮用时将饮料含在口中（p = 0.035；比值比 = 1.82，95%置信区间：1.26 - 2.63）以及经常吃零食（p = 0.041；比值比 = 1.58，95%置信区间：1.18 - 2.10）与侵蚀性牙齿磨损显著相关。
未来的研究应使用标准化问卷来评估侵蚀性牙齿磨损及其潜在风险因素（国际前瞻性系统评价注册库：CRD4202339776）。
