Menini Maria, Canullo Luigi, Iacono Roberta, Triestino Alessio, Caponio Vito Carlo Alberto, Savadori Paolo, Pesce Paolo, Pedetta Andrea, Guerra Fabrizio
Department of Surgical Sciences (DISC), University of Genoa, Largo R. Benzi 10, 16132 Genoa, Italy.
Department of Oral and Maxillo-Facial Sciences, "Sapienza" University of Rome, Via Caserta 6, 00161 Rome, Italy.
Dent J (Basel). 2024 Jun 27;12(7):198. doi: 10.3390/dj12070198.
Among different therapeutic strategies proposed in the case of bone volume deficit, guided bone regeneration (GBR) is a consolidated surgical procedure. The objective of this study is to retrospectively evaluate the behavior of two bone grafts with different consistencies in the GBR procedure by measuring the volumetric tissue changes 1 year after surgery. For this retrospective analysis, 25 cases of GBR with simultaneous implant insertion were selected. A total of 13 were grafted with a porcine cortico-cancellous bone mix (CCBM group), and 12 were grafted with a pre-hydrated granulated cortico-cancellous bone mix of porcine origin blended with 20% TSV gel (Collagenated-CCBM). A collagen membrane was fixed to cover the bone defect. A total of 42 implants were placed with computer-guided surgery. Preoperative and 12-month postoperative digital impressions were used to evaluate dimensional changes. Student's t-test used for independent samples showed no statistically significant differences between the integrated distance ( = 0.995) and mean distance ( = 0.734). The mean integrated distance in the CCBM group was 41.80 (SD. 101.18) compared to a mean of 42.04 (SD. 66.71) in the Collagenated-CCBM group. Given the limitations of this study, in patients with peri-implant bone dehiscence, simple heterologous and collagenated heterologous cortico-cancellous bone grafts are suitable for filling the bone defect to promote bone regeneration, although further studies are needed.
在针对骨量不足提出的不同治疗策略中,引导骨再生(GBR)是一种成熟的外科手术。本研究的目的是通过测量术后1年的体积组织变化,回顾性评估在GBR手术中使用的两种不同质地骨移植材料的表现。对于这项回顾性分析,选择了25例同时植入种植体的GBR病例。其中13例移植了猪皮质松质骨混合材料(CCBM组),12例移植了与20%TSV凝胶混合的猪源预水合颗粒状皮质松质骨混合材料(胶原化CCBM组)。固定一层胶原膜以覆盖骨缺损。总共通过计算机引导手术植入了42枚种植体。术前和术后12个月的数字化印模用于评估尺寸变化。用于独立样本的学生t检验显示,整合距离(=0.995)和平均距离(=0.734)之间无统计学显著差异。CCBM组的平均整合距离为41.80(标准差101.18),而胶原化CCBM组的平均整合距离为42.04(标准差66.71)。鉴于本研究的局限性,在种植体周围骨裂开的患者中,单纯的异种和胶原化异种皮质松质骨移植材料适合填充骨缺损以促进骨再生,尽管还需要进一步研究。