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一只宠物兔发生颈椎间盘突出伴背侧移位

Cervical Disc Extrusion with Dorsal Migration in a Pet Rabbit.

作者信息

Porcarelli Laura, Dell'Era Elena, Collarile Tommaso, De Palma Valeria, Morara Noemi, Matiasek Kaspar, Corlazzoli Daniele

机构信息

Centro Veterinario Gregorio VII, 00165 Rome, Italy.

Section of Clinical & Comparative Neuropathology, Institute of Veterinary Pathology, Centre for Clinical Veterinary Medicine, LMU Munich, 80539 Munich, Germany.

出版信息

Vet Sci. 2024 Jul 21;11(7):328. doi: 10.3390/vetsci11070328.

DOI:10.3390/vetsci11070328
PMID:39058012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11281693/
Abstract

An 8-year-old rabbit presented with a 5-day history of acute difficulty in walking. Neurological examination revealed tetraparesis, proprioceptive deficits in both pelvic limbs and the right thoracic limb, decreased withdrawal reflex on the right thoracic limb and hyperreflexia in the pelvic limbs. A cervico-thoracic (C6-T2) localization was suspected. Computer tomography (CT) and magnetic resonance imaging (MRI) scans were performed, revealing a right dorsolateral extradural lesion at the C6-C7 intervertebral disc space. Additionally, meningeal and paravertebral contrast enhancement was observed on MRI, while periosteal reaction was evident at the right C6-C7 facet joint on CT. The findings were primarily consistent with spinal cord compression due to the presence of extruded disc material. Following conservative treatment failure, a right-sided C6-C7 hemilaminectomy was performed to remove the compression and sample the extradural material. Histological examination confirmed the presence of degenerated and partially mineralized disc material mixed with granulation tissue. This is the first reported case of cervical disc extrusion in a rabbit, confirmed by histological examination.

摘要

一只8岁的兔子出现了5天的急性行走困难病史。神经学检查发现四肢轻瘫,双侧后肢和右前肢本体感觉缺失,右前肢的退缩反射减弱以及后肢反射亢进。怀疑病变位于颈胸段(C6-T2)。进行了计算机断层扫描(CT)和磁共振成像(MRI)扫描,结果显示在C6-C7椎间盘间隙有一个右侧背外侧硬膜外病变。此外,MRI上观察到脑膜和椎旁有对比增强,而CT上右侧C6-C7小关节处有明显的骨膜反应。这些发现主要与由于椎间盘物质突出导致的脊髓受压一致。保守治疗失败后,进行了右侧C6-C7半椎板切除术以解除压迫并获取硬膜外物质样本。组织学检查证实存在退变且部分矿化的椎间盘物质与肉芽组织混合。这是首例经组织学检查证实的兔颈椎间盘突出病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d40d/11281693/6bfe397df6ac/vetsci-11-00328-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d40d/11281693/33fd19585ef5/vetsci-11-00328-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d40d/11281693/8ab00cd5a37c/vetsci-11-00328-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d40d/11281693/6bfe397df6ac/vetsci-11-00328-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d40d/11281693/33fd19585ef5/vetsci-11-00328-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d40d/11281693/8ab00cd5a37c/vetsci-11-00328-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d40d/11281693/6bfe397df6ac/vetsci-11-00328-g003.jpg

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Current Understanding of the Genetics of Intervertebral Disc Degeneration.目前对椎间盘退变遗传学的认识。
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Low-field magnetic resonance changes in the paravertebral musculature of dogs with acute intervertebral disc extrusion.急性椎间盘突出犬椎旁肌肉组织的低场磁共振变化
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