Department of Medicine, Shandong College of Traditional Chinese Medicine, Yantai, China.
Department of Reproductive Medicine, Yantai Muping Hospital of Traditional Chinese Medicine, Yantai, China.
Medicine (Baltimore). 2024 Jul 26;103(30):e39069. doi: 10.1097/MD.0000000000039069.
Infertility can lead to significant psychological distress among women, yet the roles of hope and resilience in mitigating depressive symptoms remain inadequately explored, particularly within the Chinese context. We performed a cross-sectional observational study to investigate the psychological impacts of infertility among Chinese women as well as to discern whether hope and resilience can influence their depressive symptoms. We recruited 364 Chinese women seeking infertility treatment in the Shandong region. Participants completed validated assessments including the Hospital Anxiety and Depression Scale, Connor-Davidson Resilience Scale, and Herth Hope Index. Demographic and clinical data were also collected. We observed elevated levels of depressive symptoms and anxiety among women with infertility. Particularly, demographic factors such as an older age, rural residence, lower income, lower education, adverse life events, and longer infertility duration were associated with increased depressive symptoms. Individuals who experienced adverse life events were at a 2.42-fold increased risk of developing depressive symptoms (P = .04). Depressive symptoms were inversely correlated with both hope levels (r = -0.25; P < .05) and resilience levels (r = -0.32; P < .05). Hope levels were positively correlated with resilience (R = 0.67; P < .05). After controlling for the interaction of hope and resilience, we found that only depressive symptoms and resilience were negatively correlated. The psychological burden of infertility among Chinese women is widespread and affects many individuals from different demographic backgrounds. Interventions aimed at increasing resilience may be helpful to mitigate depressive symptoms.
不孕不育可能会给女性带来严重的心理困扰，但希望和适应力在减轻抑郁症状方面的作用在中文环境中仍未得到充分探索。我们进行了一项横断面观察性研究，旨在调查不孕不育对中国女性的心理影响，并探讨希望和适应力是否会影响她们的抑郁症状。我们招募了 364 名在山东寻求不孕不育治疗的中国女性。参与者完成了经过验证的评估，包括医院焦虑和抑郁量表、Connor-Davidson 适应力量表和 Herth 希望指数。还收集了人口统计学和临床数据。我们观察到不孕不育女性存在较高水平的抑郁症状和焦虑。特别是，人口统计学因素，如年龄较大、农村居住、收入较低、教育程度较低、不良生活事件和不孕不育时间较长，与抑郁症状增加有关。经历过不良生活事件的人患抑郁症状的风险增加了 2.42 倍（P=0.04）。抑郁症状与希望水平呈负相关（r=-0.25；P<0.05），与适应力水平呈负相关（r=-0.32；P<0.05）。希望水平与适应力呈正相关（R=0.67；P<0.05）。在控制希望和适应力的相互作用后，我们发现只有抑郁症状和适应力呈负相关。不孕不育给中国女性带来的心理负担普遍存在，影响着不同人口背景的许多人。增加适应力的干预措施可能有助于减轻抑郁症状。
