Zheng Mingxiang, Wang Hengxu, Li Chaofeng, Ouyang Yan, Yan Liyuan, Gong Fei, Li Li, Li Xihong
NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Sciences, Central South University, Changsha City 410078, China.
Imaging Department, Clinical Research Centre for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha City 410078, China.
Depress Anxiety. 2025 Jul 15;2025:2100969. doi: 10.1155/da/2100969. eCollection 2025.
This study aimed to investigate the pathways of emotional suppression among women aged 35 years and older undergoing in vitro fertilization-embryo transfer (IVF-ET) and to provide a theoretical basis for developing personalized programs to reduce emotional suppression. A convenience sample of 225 women aged ≥35 years undergoing IVF-ET at a reproductive centre between May 1st and September 30th, 2023, was selected. The participants completed a self-designed general information questionnaire, the Emotional Inhibition Scale (EIS), the Locke-Wallace Marriage Adjustment Test (MAT), and the Self-Compassion Scale (SCS). Data were analysed using SPSS 27.0 and AMOS 24.0. Normality and homogeneity of variance were assessed, with normally distributed data described as mean ± standard deviation (SD). Pearson correlation, structural equation modeling (SEM), and bootstrap resampling (5000 iterations, 95% confidence intervals [CIs]) were employed to test the mediation effects, with a bootstrap analysis used to assess the stability and significance of indirect effects through repeated sampling. The cohort comprised predominantly Han Chinese (82.2%), first-married (60.9%), urban-dwelling (60.4%) women with secondary infertility (68.0%). Over 40.0% of the total held a tertiary educational level, and 67.1% reported per capita monthly income of the family (3001-10,000 RMB). The mean emotional suppression score was 28.65 ± 6.74. Emotional suppression was negatively correlated with marital adjustment ( = -0.442, < 0.01) and self-compassion ( = -0.393, < 0.01). SEM with bootstrap validation demonstrated that marital adjustment mediated the relationship between emotional suppression and self-compassion (mediating effect proportion: 24.89%, 95% CI: -0.115 to -0.027). Marital adjustment mediates emotional suppression and self-compassion in women aged ≥35 years undergoing IVF-ET. Fostering positive marital dynamics may alleviate emotional suppression and enhance self-compassion, promoting psychological resilience during treatment. These findings support targeted interventions to improve patient satisfaction and treatment success rates.
本研究旨在探讨35岁及以上接受体外受精-胚胎移植（IVF-ET）的女性情绪抑制的途径，并为制定个性化方案以减少情绪抑制提供理论依据。选取了2023年5月1日至9月30日期间在一家生殖中心接受IVF-ET的225名年龄≥35岁的女性作为便利样本。参与者完成了一份自行设计的一般信息问卷、情绪抑制量表（EIS）、洛克-华莱士婚姻调适测试（MAT）和自我同情量表（SCS）。使用SPSS 27.0和AMOS 24.0对数据进行分析。评估数据的正态性和方差齐性，正态分布的数据以均值±标准差（SD）描述。采用Pearson相关性分析、结构方程模型（SEM）和Bootstrap重抽样（5000次迭代，95%置信区间[CIs]）来检验中介效应，通过Bootstrap分析评估间接效应在重复抽样中的稳定性和显著性。该队列主要由汉族女性（82.2%）、初婚女性（60.9%）、城市女性（60.4%）和继发性不孕女性（68.0%）组成。超过40.0%的人拥有大专及以上学历，67.1%的人报告家庭人均月收入（3001-10000元人民币）。情绪抑制的平均得分为28.65±6.74。情绪抑制与婚姻调适（r=-0.442，P<0.01）和自我同情（r=-0.393，P<0.）呈负相关。经Bootstrap验证的SEM表明，婚姻调适在情绪抑制和自我同情之间起中介作用（中介效应比例：24.89%，95% CI：-0.115至-0.027）。婚姻调适在35岁及以上接受IVF-ET的女性情绪抑制和自我同情之间起中介作用。培养积极的婚姻动态可能减轻情绪抑制并增强自我同情，从而在治疗期间促进心理复原力。这些发现支持有针对性的干预措施，以提高患者满意度和治疗成功率。
