The Third Affiliated Hospital of Zhengzhou University, No. 7, Kangfuqian Street, Erqi District, Zhengzhou, Henan, 450052, China.
Ann Clin Microbiol Antimicrob. 2024 Jul 26;23(1):66. doi: 10.1186/s12941-024-00712-4.
Bacillus cereus is a bacterium capable of causing late-onset neonatal sepsis. By analyzing 11 cases, this study investigates the diagnosis, treatment, and prognosis of Bacillus cereus infections, aiming to provide insights into clinical diagnosis and therapy. The study scrutinized 11 instances of late-onset neonatal sepsis, including two fatalities attributable to Bacillus cereus, one accompanied by cerebral hemorrhage. An examination and analysis of these cases' symptoms, signs, laboratory tests, and treatment processes, along with a review of related literature from 2010 to 2020, revealed a high mortality rate of 41.38% in non-gastrointestinal infections caused by Bacillus cereus. Our findings underscore the critical importance of rapid diagnosis and effective antimicrobial therapy in reducing mortality rates. Once the source of infection is identified, implementing effective infection control measures is essential.
蜡样芽胞杆菌是一种能够引起迟发性新生儿败血症的细菌。通过分析 11 例病例，本研究旨在探讨蜡样芽胞杆菌感染的诊断、治疗和预后，为临床诊断和治疗提供思路。研究对 11 例迟发性新生儿败血症病例进行了回顾性分析，其中 2 例死亡归因于蜡样芽胞杆菌，1 例伴有脑出血。对这些病例的症状、体征、实验室检查和治疗过程进行了检查和分析，并对 2010 年至 2020 年的相关文献进行了复习，结果发现，非胃肠道感染引起的蜡样芽胞杆菌感染的死亡率高达 41.38%。我们的研究结果强调了快速诊断和有效抗菌治疗对于降低死亡率的重要性。一旦确定了感染源，就必须采取有效的感染控制措施。
