Uzun Davut D, Tryjanowski Timo, Arians Nathalie, Mohr Stefan, Schmitt Felix C F, Michalski Christoph W, Weigand Markus A, Debus Juergen, Lang Kristin
Department of Anesthesiology, Medical Faculty Heidelberg, University Heidelberg, 69120 Heidelberg, Germany.
Department of Radiation Oncology, Medical Faculty Heidelberg, University Heidelberg, 69120 Heidelberg, Germany.
Cancers (Basel). 2024 Jul 15;16(14):2540. doi: 10.3390/cancers16142540.
(1) Background: Currently, no data are available in the literature investigating the influence of radiotherapy (RT) on endotracheal intubation success in patients with esophageal cancer. This study aims to evaluate the impact of RT on endotracheal intubation quality metrics in patients with esophageal cancer. (2) Methods: Patients with esophageal cancer who underwent RT followed by surgery between 2012 and 2023 at the University Hospital Heidelberg, Germany, were retrospectively analyzed. (3) Results: Fifty-five patients, predominantly males 65.5% with a mean age of 64 years, were enrolled. Overall, 81.8% of the patients had an ASA class of III, followed by 27.2% ASA II. The mean prescribed cumulative total dose to the primary tumor and lymph node metastasis was 48.2 Gy with a mean single dose of 1.8 Gy. The mean laryngeal total dose was 40.0 Gy. Direct laryngoscopy was performed in 80.0% of cases, followed by 12.1% videolaryngoscopy, and 7.2% required fiberoptic intubation. Overall, 96.4% of patients were successfully intubated on the first attempt. (4) Conclusions: It has been demonstrated that post-RT effects can increase the risk of airway management difficulties and complications. The results of our study did not indicate any evidence of impaired advanced airway management in patients with esophageal cancer who had undergone RT.
(1) 背景：目前，文献中尚无关于放疗（RT）对食管癌患者气管插管成功率影响的数据。本研究旨在评估放疗对食管癌患者气管插管质量指标的影响。(2) 方法：对2012年至2023年期间在德国海德堡大学医院接受放疗后手术的食管癌患者进行回顾性分析。(3) 结果：共纳入55例患者，以男性为主（65.5%），平均年龄64岁。总体而言，81.8%的患者美国麻醉医师协会（ASA）分级为III级，其次是27.2%的ASA II级。原发肿瘤和淋巴结转移的平均处方累积总剂量为48.2 Gy，平均单次剂量为1.8 Gy。喉部平均总剂量为40.0 Gy。80.0%的病例采用直接喉镜检查，其次是12.1%的视频喉镜检查，7.2%的患者需要纤维支气管镜插管。总体而言，96.4%的患者首次尝试插管成功。(4) 结论：已证明放疗后效应会增加气道管理困难和并发症的风险。我们的研究结果未表明接受放疗的食管癌患者在高级气道管理方面存在任何受损迹象。
