Sović Josipa, Šegović Sanja, Pavelić Božidar, Bago Ivona, Šutej Ivana, Tomašić Ivan
PhD Postgraduate Study, School of Dental Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Dental Clinic, Health Center Križevci, 48260 Križevci, Croatia.
Antibiotics (Basel). 2024 Jul 12;13(7):645. doi: 10.3390/antibiotics13070645.
In response to the global trend of decreasing antibiotic usage, this study aimed to evaluate the nature and frequency of antibiotic prescriptions in conjunction with endodontic therapy in Croatia and to assess the attitudes of Croatian dental practitioners towards the endodontic treatment of patients susceptible to bacterial endocarditis. A survey questionnaire was sent to all dental practitioners in Croatia, achieving a response rate of 27%. The most frequently prescribed antibiotic was penicillin with clavulanic acid (63.4%), while standalone penicillin was less prevalent (18.6%). For patients exhibiting penicillin allergies, 90% of respondents indicated clindamycin as their preferred alternative. Antibiotics were mostly prescribed for localized acute apical abscesses without fever, followed by prophylaxis for infectious endocarditis and cellulitis. Only 1.3% of the respondents reported frequent antibiotic prescriptions without accompanying local treatment. While a substantial proportion of surveyed practitioners professed familiarity with the latest guidelines for antibiotic prophylaxis, their choice of antibiotics did not consistently reflect this claim. Most respondents conducted endodontic procedures on patients at risk of bacterial endocarditis. The findings highlight a need for targeted continuing education for dental practitioners in the Republic of Croatia, ensuring their practices align with current guidelines and global trends in antibiotic prescription.
为响应全球抗生素使用量下降的趋势，本研究旨在评估克罗地亚根管治疗中抗生素处方的性质和频率，并评估克罗地亚牙科从业者对易患细菌性心内膜炎患者进行根管治疗的态度。向克罗地亚所有牙科从业者发送了一份调查问卷，回复率为27%。最常开具的抗生素是含克拉维酸的青霉素（63.4%），而单独使用青霉素的情况较少见（18.6%）。对于对青霉素过敏的患者，90%的受访者表示克林霉素是他们首选的替代药物。抗生素大多用于无发热的局限性急性根尖脓肿，其次是感染性心内膜炎和蜂窝织炎的预防。只有1.3%的受访者报告在没有相应局部治疗的情况下频繁开具抗生素。虽然很大一部分接受调查的从业者声称熟悉抗生素预防的最新指南，但他们选择的抗生素并不总是与这一说法相符。大多数受访者对有细菌性心内膜炎风险的患者进行了根管治疗。研究结果凸显了克罗地亚共和国需要针对牙科从业者开展有针对性的继续教育，确保他们的做法符合当前指南和抗生素处方的全球趋势。
