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注意力缺陷/多动障碍样犬的新进展

New Advances in Attention-Deficit/Hyperactivity Disorder-like Dogs.

作者信息

González-Martínez Ángela, Muñiz de Miguel Susana, Diéguez Francisco Javier

机构信息

Veterinary Teaching Hospital Rof Codina, Santiago de Compostela University, 27002 Lugo, Spain.

Anatomy, Animal Production and Clinical Veterinary Sciences Departament, Santiago de Compostela University, 27002 Lugo, Spain.

出版信息

Animals (Basel). 2024 Jul 14;14(14):2067. doi: 10.3390/ani14142067.

DOI:10.3390/ani14142067
PMID:39061529
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11273832/
Abstract

Similar to humans, dogs could suffer an Attention-Deficit/Hyperactivity Disorder-like syndrome (ADHD-like). In fact, several studies highlight the use of dogs as a model for studying ADHD. This condition entails behavioral problems expressed through impulsivity, attention issues, hyperactivity, and/or aggression, compromising the quality of life for both the caregiver and the dog. The pathophysiology of ADHD-like is complex and is associated with dysregulation of various neurotransmitters such as serotonin and dopamine. The expression of ADHD-like behavior in dogs would appear to depend on a classical gene-environment interaction as is the case with many neurological disorders in humans. In addition to the described symptomatology, ADHD-like dogs can exhibit strong comorbidities with compulsive behaviors, aggressiveness, inappropriate elimination and fearfulness, in addition to epilepsy, foreign body ingestion, and pruritus. In spite of the fact that there is no veterinary consensus about the diagnosis of ADHD-like, some validated questionnaires could be helpful, but these cannot be used as a unique diagnostic tool. The use of drugs, such as fluoxetine, in addition to an adequate environmental enrichment, relaxation protocols, and behavior modification can achieve an adequate quality of life for both the dog and caregivers.

摘要

与人类相似,狗也可能患上类似注意力缺陷多动障碍的综合征(ADHD样综合征)。事实上,多项研究强调了将狗作为研究ADHD的模型。这种情况会导致通过冲动、注意力问题、多动和/或攻击行为表现出来的行为问题,影响照顾者和狗的生活质量。ADHD样综合征的病理生理学很复杂,与血清素和多巴胺等多种神经递质的失调有关。狗身上ADHD样行为的表现似乎取决于经典的基因-环境相互作用,人类的许多神经疾病也是如此。除了上述症状外,ADHD样的狗除了癫痫、吞食异物和瘙痒外,还可能表现出与强迫行为、攻击性、不适当排泄和恐惧相关的强烈共病。尽管对于ADHD样综合征的诊断没有兽医界的共识,但一些经过验证的问卷可能会有所帮助,但这些问卷不能用作唯一的诊断工具。使用药物,如氟西汀,再加上适当的环境丰富化、放松方案和行为矫正,可以为狗和照顾者实现足够的生活质量。

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本文引用的文献

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Towards an Objective Measurement Tool for ADHD-like Traits in Family Dogs: A Comprehensive Test Battery.迈向用于测量家犬类多动症特征的客观测量工具:一套综合测试组。
Animals (Basel). 2024 Jun 21;14(13):1841. doi: 10.3390/ani14131841.
2
The Psychology of Atopic Dermatitis.特应性皮炎的心理学
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Development of a human-analogue, 3-symptom domain Dog ADHD and Functionality Rating Scale (DAFRS).开发一种人类模拟的、三症状域犬 ADHD 和功能评定量表(DAFRS)。
Sci Rep. 2024 Jan 20;14(1):1808. doi: 10.1038/s41598-024-51924-9.
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Epilepsy is more than a simple seizure disorder: Parallels between human and canine cognitive and behavioural comorbidities.癫痫不仅仅是一种简单的发作性疾病:人类与犬类认知及行为共病之间的相似之处。
Vet J. 2024 Feb;303:106060. doi: 10.1016/j.tvjl.2023.106060. Epub 2023 Dec 19.
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Associations of Atopic Dermatitis with Attention Deficit/Hyperactivity Disorder and Autism Spectrum Disorder: A Systematic Review and Meta-Analysis.特应性皮炎与注意力缺陷/多动障碍及自闭症谱系障碍的关联:一项系统评价与荟萃分析。
Dermatology. 2024;240(1):13-25. doi: 10.1159/000533366. Epub 2023 Nov 8.
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Efficacy and safety of selegiline across different psychiatric disorders: A systematic review and meta-analysis of oral and transdermal formulations.不同精神障碍中单胺氧化酶 B 抑制剂(司来吉兰)的疗效和安全性:口服和透皮制剂的系统评价和荟萃分析。
Eur Neuropsychopharmacol. 2023 Jul;72:60-78. doi: 10.1016/j.euroneuro.2023.03.012. Epub 2023 Apr 21.
7
Serotonin and Dopamine Blood Levels in ADHD-Like Dogs.患类似注意力缺陷多动障碍犬只的血清素和多巴胺血液水平
Animals (Basel). 2023 Mar 13;13(6):1037. doi: 10.3390/ani13061037.
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Owner-rated hyperactivity/impulsivity is associated with sleep efficiency in family dogs: a non-invasive EEG study.主人评定的多动/冲动与家庭犬的睡眠效率有关:一项非侵入性 EEG 研究。
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