Rando Gabriela Mendonça, Ambrosio Eloá Cristina Passucci, Jorge Paula Karine, Sforza Chiarella, Menezes Márcio, de Almeida Ana Lúcia Pompeia Fraga, Soares Simone, Dalben Gisele Silva, Tonello Cristiano, Carrara Cleide Felício Carvalho, Machado Maria Aparecida Andrade Moreira, Oliveira Thais Marchini
Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, Brazil.
Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru 17012-900, Brazil.
Children (Basel). 2024 Jul 5;11(7):824. doi: 10.3390/children11070824.
This investigation aimed to assess the optimal timing for lip repair in children with cleft lip and palate via 3D anthropometric analysis to evaluate their maxillofacial structures.
The sample comprised 252 digitized dental models, divided into groups according to the following timing of lip repair: G1 (n = 50): 3 months; G2 (n = 50): 5 and 6 months; G3 (n = 26): 8 and 10 months. Models were evaluated at two-time points: T1: before lip repair; T2: at 5 years of age. Linear measurements, area, and Atack index were analyzed.
At T1, the intergroup analysis revealed that G1 had statistically significant lower means of I-C', I-C, C-C', and the sum of the segment areas compared to G2 ( = 0.0140, = 0.0082, = 0.0004, < 0.0001, respectively). In addition, there was a statistically significant difference when comparing the cleft area between G2 and G3 ( = 0.0346). At T2, the intergroup analysis revealed that G1 presented a statistically significant mean I-C' compared to G3 ( = 0.0461). In the I-CC' length analysis, G1 and G3 showed higher means when compared to G2 ( = 0.0039). The I-T' measurement was statistically higher in G1 than in G2 ( = 0.0251). In the intergroup growth rate analysis, G1 and G2 showed statistically significant differences in the I-C' measurement compared to G3 ( = 0.0003). In the analysis of the Atack index, there was a statistically significant difference between G1 and the other sample sets ( < 0.0001).
Children who underwent surgery later showed better results in terms of the growth and development of the dental arches.
本研究旨在通过三维人体测量分析评估唇腭裂患儿唇修复的最佳时机，以评估其颌面结构。
样本包括252个数字化牙科模型，根据以下唇修复时机分为几组：G1（n = 50）：3个月；G2（n = 50）：5和6个月；G3（n = 26）：8和10个月。在两个时间点对模型进行评估：T1：唇修复前；T2：5岁时。分析线性测量、面积和阿塔克指数。
在T1时，组间分析显示，与G2相比，G1的I-C'、I-C、C-C'以及节段面积总和的均值在统计学上显著更低（分别为 = 0.0140、 = 0.0082、 = 0.0004、 < 0.0001）。此外，比较G2和G3之间的裂隙面积时存在统计学显著差异（ = 0.0346）。在T2时，组间分析显示，与G3相比，G1的I-C'均值在统计学上显著更高（ = 0.0461）。在I-CC'长度分析中，与G2相比，G1和G3的均值更高（ = 0.0039）。G1的I-T'测量值在统计学上高于G2（ = 0.0251）。在组间生长率分析中，与G3相比，G1和G2在I-C'测量上显示出统计学显著差异（ = 0.0003）。在阿塔克指数分析中，G1与其他样本组之间存在统计学显著差异（ < 0.0001）。
手术时间较晚的儿童在牙弓生长发育方面显示出更好的结果。
