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典型与自闭症谱系障碍(ASD)患病可能性增加的婴儿的物体探索与操作:综述

Object Exploration and Manipulation in Infants at Typical vs. Elevated Likelihood for ASD: A Review.

作者信息

Focaroli Valentina, Taffoni Fabrizio, Velardi Andrea, Caravale Barbara, Keller Flavio

机构信息

Department of Economic, Psychological and Communication Sciences, Niccolò Cusano University, 00166 Rome, Italy.

CREO LAB, Advanced Robotics and Human Centred-Technologies Laboratory, Campus Bio-Medico University, 00128 Rome, Italy.

出版信息

Children (Basel). 2024 Jul 5;11(7):825. doi: 10.3390/children11070825.

DOI:10.3390/children11070825
PMID:39062274
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11276247/
Abstract

The present review considers the growing body of literature on fine motor skills in infants at elevated genetic likelihood (EL) for autism spectrum disorder (ASD). This area of study aims to identify crucial motor markers associated with the disorder, facilitating earlier and more accurate identification of ASD, using various experimental methodologies, including standardized assessments, observational measures, and technological tools. The reviewed evidence revealed distinct developmental trajectories in EL infants, marked by differences in fine motor skills and exploratory behaviors compared to typically developing infants. We discuss the developmental trajectory of fine motor skills in infants and their predictive value for later ASD diagnosis, highlighting the significance of fine motor skills as early indicators of ASD risk in infants and emphasizing the need for further research to elucidate their predictive value and underlying mechanisms.

摘要

本综述探讨了关于自闭症谱系障碍(ASD)遗传易感性升高(EL)的婴儿精细运动技能的文献不断增加的情况。该研究领域旨在通过使用各种实验方法,包括标准化评估、观察性测量和技术工具,识别与该疾病相关的关键运动标志物,以促进对ASD的更早、更准确的识别。综述证据显示,EL婴儿有独特的发育轨迹,其精细运动技能和探索行为与正常发育的婴儿存在差异。我们讨论了婴儿精细运动技能的发育轨迹及其对后期ASD诊断的预测价值,强调了精细运动技能作为婴儿ASD风险早期指标的重要性,并强调需要进一步研究以阐明其预测价值和潜在机制。

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本文引用的文献

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Altered motor learning and coordination in mouse models of autism spectrum disorder.自闭症谱系障碍小鼠模型中运动学习与协调能力的改变
Front Cell Neurosci. 2023 Nov 8;17:1270489. doi: 10.3389/fncel.2023.1270489. eCollection 2023.
2
Case report: An evaluation of early motor skills in an infant later diagnosed with autism.病例报告:对一名后来被诊断为自闭症的婴儿早期运动技能的评估。
Front Psychiatry. 2023 Jun 19;14:1205532. doi: 10.3389/fpsyt.2023.1205532. eCollection 2023.
3
Object Play and Autism Spectrum Disorders Symptoms in Toddlers Aged 12-37 Month at Risk of Developmental Disorders.12至37个月有发育障碍风险的幼儿的物体游戏与自闭症谱系障碍症状
Children (Basel). 2023 Jun 1;10(6):995. doi: 10.3390/children10060995.
4
Early development in autism: How developmental cascades help us understand the emergence of developmental differences.自闭症的早期发育:发展级联如何帮助我们理解发育差异的出现。
Adv Child Dev Behav. 2023;64:109-134. doi: 10.1016/bs.acdb.2022.10.005. Epub 2022 Dec 6.
5
Prediction of autism in infants: progress and challenges.婴儿自闭症预测:进展与挑战。
Lancet Neurol. 2023 Mar;22(3):244-254. doi: 10.1016/S1474-4422(22)00407-0. Epub 2022 Nov 22.
6
Capturing the complexity of autism: Applying a developmental cascades framework.捕捉自闭症的复杂性:应用发展级联框架。
Child Dev Perspect. 2022 Mar;16(1):18-26. doi: 10.1111/cdep.12439. Epub 2022 Jan 19.
7
Developing language in a developing body, revisited: The cascading effects of motor development on the acquisition of language.发展中的身体中的语言发展:运动发展对语言习得的级联效应。
Wiley Interdiscip Rev Cogn Sci. 2022 Nov;13(6):e1626. doi: 10.1002/wcs.1626. Epub 2022 Sep 27.
8
Developmental Coordination Disorder and Most Prevalent Comorbidities: A Narrative Review.发育性协调障碍及最常见的共病:一项叙述性综述
Children (Basel). 2022 Jul 21;9(7):1095. doi: 10.3390/children9071095.
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Autism. 2023 Jan;27(1):133-144. doi: 10.1177/13623613221086448. Epub 2022 Apr 26.
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Early Motor Signs in Autism Spectrum Disorder.自闭症谱系障碍的早期运动迹象
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