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[中非卢旺达志贺氏菌病流行的3年研究。公共卫生问题及细菌学方面]

[3-year study of shigellosis epidemic in Rwanda, Central Africa. Problems of public health and bacteriological aspects].

作者信息

Vimont-Vicary P, Rogerie F

出版信息

Med Trop (Mars). 1985 Jul-Sep;45(3):235-43.

PMID:3906345
Abstract

Since 1979, the Lakes region (Kivu in Zaïre, Western Uganda, Rwanda, Burundi) has been stricken by a bacillary dysentery epidemic at S. dysenteriae type 1. Supposed to be extinct since the 1950s., this bacillus has revealed a very noticeable virulence as well by the number of registered cases (524/100.000 in 1983 at Ruhengeri-Rwanda) as its fast break through. Demographic density (from 400 to 600/km2) has played an important role and has facilitated the transition toward epidemicity. Systematic bacteriological exams on the spot has allowed prompt identification of the involved germ, antibiotics to be used, and resistance variations during the period under consideration. The role of a regional laboratory to monitor diarrheal diseases has been demonstrated as of prime importance to set up a fighting strategy at regional level.

摘要

自1979年以来,湖区(扎伊尔的基伍、乌干达西部、卢旺达、布隆迪)一直遭受1型志贺氏痢疾杆菌引起的杆菌性痢疾疫情的侵袭。这种杆菌本应自20世纪50年代起就已灭绝,但从登记病例数量(1983年在卢旺达鲁亨盖里为524/10万)及其迅速传播情况来看,它显示出了极强的毒性。人口密度(每平方公里400至600人)起到了重要作用,推动了疫情的蔓延。在当地进行的系统细菌学检查能够迅速识别相关病菌、确定所用抗生素以及观察在所研究期间的耐药性变化。事实证明,区域实验室在监测腹泻疾病方面的作用对于制定区域层面的防治策略至关重要。

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