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那不勒斯儿童急性腹泻:一项病因学研究。

Acute childhood diarrhoea in Naples: an aetiologic study.

作者信息

Caprioli A, Falbo V, Giraldi V, Ruggeri F M, Capano G, Guandalini S, Guarino A, Rubino A

出版信息

Microbiologica. 1985 Oct;8(4):329-37.

PMID:3906366
Abstract

A potential aetiologic agent was detected in the stools of 56% of 118 children hospitalized in Naples for acute diarrhoea. Rotavirus and Salmonella were the agents most commonly associated with disease, accounting for 23 and 17 percent of cases, respectively. Campylobacter jejuni, enterotoxigenic Escherichia coli, Yersinia and Shigella were less frequently isolated (total, 11% of cases). These findings fit well with the epidemiological picture described for other developed countries, except for the isolation rate of Salmonella which widely exceeds that reported in other investigations. Cytotoxic strains of E. coli and other Gram-negative bacilli were identified in the stools of 18 children; the possible pathogenic role of these strains is unknown and needs further investigation.

摘要

在那不勒斯因急性腹泻住院的118名儿童中,56%的儿童粪便中检测到一种潜在的病原体。轮状病毒和沙门氏菌是与疾病最常相关的病原体,分别占病例的23%和17%。空肠弯曲菌、产肠毒素大肠杆菌、耶尔森菌和志贺菌的分离频率较低(总计占病例的11%)。这些发现与其他发达国家描述的流行病学情况非常吻合,但沙门氏菌的分离率远远超过其他调查报道的水平。在18名儿童的粪便中鉴定出细胞毒性大肠杆菌菌株和其他革兰氏阴性杆菌;这些菌株可能的致病作用尚不清楚,需要进一步研究。

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