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头颈部感染的流行病学与管理模式,包括新冠疫情期间:在克卢日-纳波卡颌面中心进行的一项10年回顾性研究

Epidemiology and Management Paradigm of Head and Neck Infections, Including COVID-19 Pandemic Period: A 10-Year Retrospective Study in a Maxillofacial Center of Cluj-Napoca.

作者信息

Faur Cosmin Ioan, Moldovan Mădălina Anca, Paraschivescu Tino, Megieșan Sergiu, Roman Rareș Călin

机构信息

Department of Oral Radiology, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, 400006 Cluj-Napoca, Romania.

Department of Oral and Maxillofacial Surgery and Implantology, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, 400006 Cluj-Napoca, Romania.

出版信息

J Clin Med. 2024 Jul 10;13(14):4046. doi: 10.3390/jcm13144046.

DOI:10.3390/jcm13144046
PMID:39064086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11277223/
Abstract

The management of odontogenic infections varies across the globe. To shed light on the subject, this study delves into the practices of the Oral and Maxillofacial Department at Cluj-Napoca County Hospital. This comprehensive retrospective analysis of 10 years of clinical experience covered a range of factors, including demographics, clinical and investigations factors, medical and surgical treatment approaches, and follow-up. Additionally, the study examined the change in trends over the course of the COVID-19 pandemic. While head and neck infection occurrence had a decreasing trend before the COVID-19 pandemic, during the pandemic era the number of patients almost doubled. The infections were prevalent in the submandibular space, teeth being the prevalent cause. Young adults are prone to suffer from odontogenic infections. High levels of C reactive protein, ASA II-IV risk, and hepatic dysfunction indicated a longer time of hospitalization. The majority of antibiograms were negative, and the positive ones indicated Streptococcus and Staphylococcus species as prevalent pathogens. Extra- or intraoral surgical drainage and wide-spectrum antibiotics proved to be the workhorse for odontogenic infections. This study advances our understanding of oral and maxillofacial surgery and offers actionable strategies for improving patient outcomes in similar healthcare institutions worldwide.

摘要

牙源性感染的管理在全球各地各不相同。为了阐明这一主题,本研究深入探讨了克卢日-纳波卡县医院口腔颌面科的治疗方法。这项对10年临床经验的全面回顾性分析涵盖了一系列因素,包括人口统计学、临床和检查因素、药物和手术治疗方法以及随访情况。此外,该研究还考察了新冠疫情期间的趋势变化。在新冠疫情之前,头颈部感染的发生率呈下降趋势,但在疫情期间,患者数量几乎翻了一番。感染主要发生在下颌下间隙,牙齿是主要病因。年轻人更容易患上牙源性感染。高浓度的C反应蛋白、ASA II-IV级风险和肝功能障碍表明住院时间较长。大多数药敏试验结果为阴性,阳性结果表明链球菌和葡萄球菌是主要病原体。口外或口内手术引流以及广谱抗生素被证明是治疗牙源性感染的主要手段。这项研究增进了我们对口腔颌面外科的理解,并为全球类似医疗机构改善患者治疗效果提供了可行的策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d0/11277223/a6738d056902/jcm-13-04046-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d0/11277223/49f58713f597/jcm-13-04046-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d0/11277223/2038b03247d0/jcm-13-04046-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d0/11277223/a5615cdde1a6/jcm-13-04046-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d0/11277223/a6738d056902/jcm-13-04046-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d0/11277223/49f58713f597/jcm-13-04046-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d0/11277223/2038b03247d0/jcm-13-04046-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d0/11277223/a5615cdde1a6/jcm-13-04046-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d0/11277223/a6738d056902/jcm-13-04046-g004.jpg

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本文引用的文献

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The COVID-19 pandemic and its possible impact on the treatment of odontogenic and intraoral abscesses.COVID-19 大流行及其对牙源性和口腔内脓肿治疗的可能影响。
Head Face Med. 2023 Aug 19;19(1):36. doi: 10.1186/s13005-023-00381-2.
2
Evolution of the treatment of severe odontogenic infections over 50 years: A comprehensive review.50年来严重牙源性感染治疗方法的演变:一项全面综述。
J Taibah Univ Med Sci. 2022 Sep 15;18(2):225-233. doi: 10.1016/j.jtumed.2022.08.008. eCollection 2023 Apr.
3
The Role of C-Reactive Protein and Neutrophil to Lymphocyte Ratio in Predicting the Severity of Odontogenic Infections in Adult Patients.
C 反应蛋白和中性粒细胞与淋巴细胞比值在预测成年患者牙源性感染严重程度中的作用。
Medicina (Kaunas). 2022 Dec 22;59(1):20. doi: 10.3390/medicina59010020.
4
Complications of Severe Odontogenic Infections: A Review.重度牙源性感染的并发症:综述
Biology (Basel). 2022 Dec 8;11(12):1784. doi: 10.3390/biology11121784.
5
Odontogenic Infection Pathway to the Parapharyngeal Space: CT Imaging Assessment.牙源性感染至咽旁间隙的途径:CT影像评估
J Maxillofac Oral Surg. 2022 Mar;21(1):235-239. doi: 10.1007/s12663-020-01401-3. Epub 2020 Jun 26.
6
Multifunctional Irrigation-Assisted Vacuum Drainage versus Traditional Drainage in the Treatment of Odontogenic Deep Fascial Infection: A Retrospective Cohort Study.多功能冲洗辅助负压引流与传统引流治疗牙源性深部筋膜间隙感染的回顾性队列研究
Infect Drug Resist. 2021 Sep 2;14:3571-3580. doi: 10.2147/IDR.S326300. eCollection 2021.
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Severe Odontogenic Infections during Pregnancy and Related Adverse Outcomes. Case Report and Systematic Literature Review.妊娠期严重牙源性感染及相关不良结局。病例报告与系统文献综述
Trop Med Infect Dis. 2021 Jun 21;6(2):106. doi: 10.3390/tropicalmed6020106.
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The role of diabetes mellitus on the formation of severe odontogenic abscesses-a retrospective study.糖尿病对颌骨深部脓肿形成的作用:一项回顾性研究。
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