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头颈部感染的流行病学与管理模式,包括新冠疫情期间:在克卢日-纳波卡颌面中心进行的一项10年回顾性研究

Epidemiology and Management Paradigm of Head and Neck Infections, Including COVID-19 Pandemic Period: A 10-Year Retrospective Study in a Maxillofacial Center of Cluj-Napoca.

作者信息

Faur Cosmin Ioan, Moldovan Mădălina Anca, Paraschivescu Tino, Megieșan Sergiu, Roman Rareș Călin

机构信息

Department of Oral Radiology, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, 400006 Cluj-Napoca, Romania.

Department of Oral and Maxillofacial Surgery and Implantology, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, 400006 Cluj-Napoca, Romania.

出版信息

J Clin Med. 2024 Jul 10;13(14):4046. doi: 10.3390/jcm13144046.

Abstract

The management of odontogenic infections varies across the globe. To shed light on the subject, this study delves into the practices of the Oral and Maxillofacial Department at Cluj-Napoca County Hospital. This comprehensive retrospective analysis of 10 years of clinical experience covered a range of factors, including demographics, clinical and investigations factors, medical and surgical treatment approaches, and follow-up. Additionally, the study examined the change in trends over the course of the COVID-19 pandemic. While head and neck infection occurrence had a decreasing trend before the COVID-19 pandemic, during the pandemic era the number of patients almost doubled. The infections were prevalent in the submandibular space, teeth being the prevalent cause. Young adults are prone to suffer from odontogenic infections. High levels of C reactive protein, ASA II-IV risk, and hepatic dysfunction indicated a longer time of hospitalization. The majority of antibiograms were negative, and the positive ones indicated Streptococcus and Staphylococcus species as prevalent pathogens. Extra- or intraoral surgical drainage and wide-spectrum antibiotics proved to be the workhorse for odontogenic infections. This study advances our understanding of oral and maxillofacial surgery and offers actionable strategies for improving patient outcomes in similar healthcare institutions worldwide.

摘要

牙源性感染的管理在全球各地各不相同。为了阐明这一主题,本研究深入探讨了克卢日-纳波卡县医院口腔颌面科的治疗方法。这项对10年临床经验的全面回顾性分析涵盖了一系列因素,包括人口统计学、临床和检查因素、药物和手术治疗方法以及随访情况。此外,该研究还考察了新冠疫情期间的趋势变化。在新冠疫情之前,头颈部感染的发生率呈下降趋势,但在疫情期间,患者数量几乎翻了一番。感染主要发生在下颌下间隙,牙齿是主要病因。年轻人更容易患上牙源性感染。高浓度的C反应蛋白、ASA II-IV级风险和肝功能障碍表明住院时间较长。大多数药敏试验结果为阴性,阳性结果表明链球菌和葡萄球菌是主要病原体。口外或口内手术引流以及广谱抗生素被证明是治疗牙源性感染的主要手段。这项研究增进了我们对口腔颌面外科的理解,并为全球类似医疗机构改善患者治疗效果提供了可行的策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21d0/11277223/49f58713f597/jcm-13-04046-g001.jpg

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