Department of Oral and Maxillofacial Surgery - Facial plastic Surgery, Medical Center of the Johannes Gutenberg-University of Mainz, Augustusplatz 2, 55131, Mainz, Germany.
Department of Prosthodontics, Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany.
Clin Oral Investig. 2021 Nov;25(11):6279-6285. doi: 10.1007/s00784-021-03926-4. Epub 2021 May 13.
To analyze the correlation of diabetes mellitus and hyperglycemia with severe odontogenic abscesses.
Records of all patients in the Department of Oral and Maxillofacial Surgery of the Medical Center of the Johannes Gutenberg-University who underwent inpatient treatment for severe odontogenic abscesses between 2010 and 2016 were evaluated retrospectively regarding diabetes anamnesis, maximum and fasting blood sugar count, and duration until discharge. In order to compare the numbers to a general maxillofacial group, all patients who received inpatient treatment in 2013 for any diagnosis other than an abscess of the head and neck region were analyzed as well, and the numbers were correlated.
In total, 977 abscess patients were found in the analyzed period. 7.0% of the patients had a known diagnosis of diabetes mellitus type II and 0.6% of type I. Correlation with the general group showed that abscesses were significantly more likely in diabetics as well as patients with abnormal maximum and fasting blood sugar counts. These patients also needed significantly longer inpatient treatment.
Diabetics and patients with abnormal glucose tolerance show significantly higher numbers of severe odontogenic abscesses and might therefore benefit from earlier escalation of antibiotic medication.
Severe odontogenic abscesses are one of the most frequent diagnoses in maxillofacial practice. Adjusting the therapeutic approach for diabetics or patients with abnormal blood sugar counts might help to prevent the development of abscesses.
分析糖尿病和高血糖与严重牙源性脓肿的相关性。
回顾性分析 2010 年至 2016 年间在约翰内斯·古腾堡-美因茨大学医学中心口腔颌面外科接受住院治疗的所有严重牙源性脓肿患者的病历，包括糖尿病病史、最大血糖和空腹血糖计数以及出院时间。为了将这些数字与一般的颌面外科患者进行比较，还分析了 2013 年因头颈部区域以外的任何诊断而接受住院治疗的所有患者的数字，并进行了相关性分析。
在分析期间共发现 977 例脓肿患者。7.0%的患者有 II 型糖尿病的已知诊断，0.6%的患者有 I 型糖尿病。与一般组的相关性表明，糖尿病患者以及最大和空腹血糖计数异常的患者发生脓肿的可能性明显更高。这些患者也需要更长的住院治疗时间。
糖尿病患者和血糖耐量异常的患者出现严重牙源性脓肿的数量明显更高，因此可能受益于更早地升级抗生素治疗。
严重牙源性脓肿是颌面外科最常见的诊断之一。调整糖尿病或血糖计数异常患者的治疗方法可能有助于预防脓肿的发生。
