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模拟深海潜水后,麻醉性氮气效应持续存在。

Narcotic Nitrogen Effects Persist after a Simulated Deep Dive.

机构信息

Hyperbaric Oxygen Therapy (HBO), University Hospital Düsseldorf, 40225 Düsseldorf, Germany.

Klinik für Orthopädie und Unfallchirurgie Evangelisches Krankenhaus, 45468 Mülheim/Ruhr, Germany.

出版信息

Medicina (Kaunas). 2024 Jul 2;60(7):1083. doi: 10.3390/medicina60071083.

Abstract

: Scuba divers often experience persistent inert gas narcosis (IGN) even after surfacing. This study aimed to test the hypothesis that breathing oxygen (O) before surfacing can reduce postdive IGN. : A group of 58 experienced divers underwent a 5 min dive at a depth of 50 m in a multi-place hyperbaric chamber. They were decompressed using air (air group). Another group of 28 divers (O group) breathed 100% O during the end of decompression. Prior to and after the dive, all participants performed the Sharpened Romberg test (SRT) and a modified tweezers test. : In the air group, the number of positive SRT results increased postdive (47% vs. 67%), indicating a greater impairment in the vestibular system (Cohen's d = 0.41). In the O group, the percentage of positive SRT results remained constant at 68% both before and after the dive. In terms of the modified tweezers test, the air group showed no significant change in the number of picked beads (40 ± 9 vs. 39 ± 7), while the O group demonstrated an increase (36 ± 7 vs. 44 ± 10) (Cohen's d = 0.34). : The results reveal that the SRT revealed a negative effect of nitrogen (N) on the vestibular system in the air group. The increased number of beads picked in the O group can be attributed to the learning effect, which was hindered in the air group. Consistent with our hypothesis, breathing O during decompression appears to reduce postdive IGN.

摘要

: 潜水员在浮出水面后经常会经历持续的惰性气体麻醉(IGN)。本研究旨在验证这样一个假设,即在浮出水面前呼吸氧气(O)可以减少潜水后的 IGN。 : 一组 58 名有经验的潜水员在多座位高压舱中以 50 米的深度进行了 5 分钟的潜水。他们使用空气(空气组)进行减压。另一组 28 名潜水员(O 组)在减压结束时呼吸 100%的 O。在潜水前后,所有参与者都进行了锐化 Romberg 测试(SRT)和改良镊子测试。 : 在空气组中,SRT 的阳性结果数量在潜水后增加(47%对 67%),表明前庭系统受损更大(Cohen's d = 0.41)。在 O 组中,SRT 的阳性结果百分比在潜水前后均保持在 68%不变。就改良镊子测试而言,空气组挑出的珠子数量没有明显变化(40 ± 9 对 39 ± 7),而 O 组则有所增加(36 ± 7 对 44 ± 10)(Cohen's d = 0.34)。 : 结果表明,SRT 揭示了空气组中氮(N)对前庭系统的负面影响。O 组中挑出的珠子数量增加归因于学习效应,而空气组中学习效应受到阻碍。与我们的假设一致,在减压过程中呼吸 O 似乎可以减少潜水后的 IGN。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ece/11278881/e5dae669a254/medicina-60-01083-g001.jpg

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