Division of Transplantation, Department of Surgery, University of Illinois at Chicago, Chicago, IL, USA.
Division of Transplantation, Department of Surgery, University of Illinois at Chicago, Chicago, IL, USA.
Gastroenterol Clin North Am. 2024 Sep;53(3):441-452. doi: 10.1016/j.gtc.2023.12.005. Epub 2024 Jan 16.
This study explores intestinal transplantation (ITx) as a viable treatment option for intestinal failure (IF). Historical development, donor and recipient considerations, surgical techniques, immunosuppression, and outcomes, are reviewed with particular emphasis to the value of living donor ITx. The review highlights the evolution of ITx and emphasizes the ongoing need for patient-specific selection processes. In the realm of pediatric ITx, the article underlines the significance of early intervention to mitigate IF-related liver disease. Overall, it provides a comprehensive overview of this life-saving procedure.
本研究探讨了肠移植(ITx)作为治疗肠衰竭(IF)的可行方法。本文回顾了 ITx 的历史发展、供者和受者的考虑因素、手术技术、免疫抑制以及结果,并特别强调了活体供者 ITx 的价值。本文强调了 ITx 的发展演变,并强调了持续需要针对患者的选择过程。在儿科 ITx 领域,本文强调了早期干预以减轻 IF 相关肝病的重要性。总的来说,本文提供了对这种救命手术的全面概述。